Introduction：Basic information about CAS 20344-46-1|Luteollin 5-glucoside, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Luteollin 5-glucoside |
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| CAS Number | 20344-46-1 | Molecular Weight | 448.377 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 864.2±65.0 °C at 760 mmHg |
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| Molecular Formula | C21H20O11 | Melting Point | 260-263℃ |
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| MSDS | / | Flash Point | 305.8±27.8 °C |
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Names
| Name | 2-(3,4-dihydroxyphenyl)-7-hydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one |
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| Synonym | More Synonyms |
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Luteollin 5-glucoside BiologicalActivity
| Description | Luteolin 5-O-glucoside, a major flavonoidfrom Cirsium maackii, possesses anti-inflammatory activity. Luteolin 5-O-glucoside inhibits LPS-induced NO production and t-BHP-induced ROS generation. Luteolin 5-O-glucoside suppresses the expression of iNOS and COX-2 in macrophages[1]. |
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| Related Catalog | Signaling Pathways >>Immunology/Inflammation >>NO SynthaseResearch Areas >>Inflammation/Immunology |
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| In Vitro | Luteolin 5-O-glucoside, at a non-toxic concentration, inhibits LPS-induced NO production and t-BHP-induced ROS generation in a dose-dependent manner in RAW 264.7 cells. Luteolin 5-O-glucoside also suppresses the expression of iNOS and COX-2 in LPS-stimulated macrophages[1]. |
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| References | [1]. Anti-inflammatory activity of Korean thistle Cirsium maackii and its major flavonoid, luteolin 5-O-glucoside.Food Chem Toxicol. 2012 Jun;50(6):2171-9. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 864.2±65.0 °C at 760 mmHg |
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| Melting Point | 260-263℃ |
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| Molecular Formula | C21H20O11 |
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| Molecular Weight | 448.377 |
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| Flash Point | 305.8±27.8 °C |
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| Exact Mass | 448.100555 |
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| PSA | 190.28000 |
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| LogP | 0.13 |
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| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
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| Index of Refraction | 1.740 |
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| InChIKey | KBGKQZVCLWKUDQ-QNDFHXLGSA-N |
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| SMILES | O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(OC3OC(CO)C(O)C(O)C3O)c12 |
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Safety Information
Customs
| HS Code | 2932999099 |
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| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Luteolin-5-O-b-D-glucopyranoside |
| 2-(3,4-Dihydroxyphenyl)-5-(b-D-glucopyranosyloxy)-7-hydroxy-4H-1-benzopyran-4-one |
| Luteolin-5-O-glucopyranoside |
| 2-(3,4-Dihydroxyphenyl)-7-hydroxy-4-oxo-4H-chromen-5-yl β-D-glucopyranoside |
| Luteolin-5-O-β-D-glucopyranoside |
| Luteollin 5-glucoside |
| 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5-(β-D-glucopyranosyloxy)-7-hydroxy- |
| galuteolin |
| luteolin 5-O-β-D-glucopyranosyl |
