CAS 123457-83-0|4-(MALEINIMIDO)PHENYL ISOCYANATE

Introduction:Basic information about CAS 123457-83-0|4-(MALEINIMIDO)PHENYL ISOCYANATE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name4-(MALEINIMIDO)PHENYL ISOCYANATE
CAS Number123457-83-0Molecular Weight214.177
Density1.3±0.1 g/cm3Boiling Point375.4±25.0 °C at 760 mmHg
Molecular FormulaC11H6N2O3Melting Point120-125ºC
MSDSChineseUSAFlash Point180.8±23.2 °C
Symbol
GHS07, GHS08
Signal WordDanger

Names

NameN-(4-Isocyanatophenyl)maleimide PMPI
SynonymMore Synonyms

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point375.4±25.0 °C at 760 mmHg
Melting Point120-125ºC
Molecular FormulaC11H6N2O3
Molecular Weight214.177
Flash Point180.8±23.2 °C
Exact Mass214.037842
PSA66.81000
LogP1.45
Vapour Pressure0.0±0.8 mmHg at 25°C
Index of Refraction1.641
InChIKeyOJQSISYVGFJJBY-UHFFFAOYSA-N
SMILESO=C=Nc1ccc(N2C(=O)C=CC2=O)cc1
Storage condition2-8°C

Safety Information

Symbol
GHS07, GHS08
Signal WordDanger
Hazard StatementsH302-H312-H315-H317-H319-H332-H334-H335
Precautionary StatementsP261-P280-P305 + P351 + P338-P342 + P311
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard CodesXn
Risk PhrasesR20/21/22
Safety PhrasesS22
RIDADRNONH for all modes of transport

Articles4

More Articles
p-maleimidophenyl isocyanate: a novel heterobifunctional linker for hydroxyl to thiol coupling.

Bioconjug. Chem. 4 , 212, (1993)

p-Maleimidophenyl isocyanate (PMPI, 1) is a heterobifunctional cross-linking agent useful for thiol to hydroxyl coupling. Several maleimide-activated compounds were prepared and characterized and then...

Cys-93-betabeta-succinimidophenyl polyethylene glycol 2000 hemoglobin A. Intramolecular cross-bridging of hemoglobin outside the central cavity.

J. Biol. Chem. 275 , 5527, (2000)

Bis(maleidophenyl)-PEG2000 (Bis-Mal-PEG2000), a new bifunctional protein cross-linker targeted to sulfhydryl groups, introduces intra-tetrameric cross-links into oxy-HbA in nearly quantitative yields....

Synthesis of enzyme-degradable, peptide-cross-linked dextran hydrogels.

Bioconjug. Chem. 18(3) , 874-85, (2007)

Hydrogels derived from synthetic polymers have been previously engineered to degrade under the activity of matrix metalloproteinases (MMPs). It is believed that these systems can act as extracellular-...

Synonyms

4-(Maleinimido)phenyl isocyanate
1-(4-Isocyanatophenyl)-1H-pyrrole-2,5-dione
1-(4-isocyanatophenyl)pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 1-(4-isocyanatophenyl)-
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