Introduction：Basic information about CAS 120443-16-5|Verlukast, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Verlukast |
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| CAS Number | 120443-16-5 | Molecular Weight | 515.087 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 712.3±60.0 °C at 760 mmHg |
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| Molecular Formula | C26H27ClN2O3S2 | Melting Point | / |
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| MSDS | / | Flash Point | 384.6±32.9 °C |
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Names
| Name | 3-[(R)-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-[3-(dimethylamino)-3-oxopropyl]sulfanylmethyl]sulfanylpropanoic acid |
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| Synonym | More Synonyms |
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Verlukast BiologicalActivity
| Description | Verlukast is a potent, selective, and orally active antagonist of leukotriene receptor. Verlukast has the potential for the research of asthma[1]. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Leukotriene ReceptorResearch Areas >>Inflammation/Immunology |
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| Target | leukotriene receptor[1] |
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| References | [1]. Dahlén B, et al. Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects. Thorax. 1993;48(12):1205-1210. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 712.3±60.0 °C at 760 mmHg |
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| Molecular Formula | C26H27ClN2O3S2 |
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| Molecular Weight | 515.087 |
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| Flash Point | 384.6±32.9 °C |
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| Exact Mass | 514.115173 |
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| PSA | 121.10000 |
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| LogP | 5.93 |
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| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
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| Index of Refraction | 1.687 |
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| InChIKey | AXUZQJFHDNNPFG-LHAVAQOQSA-N |
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| SMILES | CN(C)C(=O)CCSC(SCCC(=O)O)c1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1 |
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Synonyms
| 3-{[(R)-{3-[(E)-2-(7-Chloroquinolin-2-yl)vinyl]phenyl}{[3-(dimethylamino)-3-oxopropyl]sulfanyl}methyl]sulfanyl}propanoic acid |
| Propanoic acid, 3-[[(R)-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]- |
| MK 679 |
| 3-(((aR)-m-((E)-2-(7-Chloro-2-quinolyl)vinyl)-a-((2-(dimethylcarbamoyl)ethyl)thio)benzyl)thio)propionic Acid |
| 3-{[(R)-{3-[(E)-2-(7-Chloro-2-quinolinyl)vinyl]phenyl}{[3-(dimethylamino)-3-oxopropyl]sulfanyl}methyl]sulfanyl}propanoic acid |
| Verlukastum |
| (R-(E))-3-(((3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)((3-(dimethylamino)-3-oxopropyl)thio)methyl)thio)propanoic Acid |
| 3-(((αR)-m-((E)-2-(7-Chloro-2-quinolyl)vinyl)-α-((2-(dimethylcarbamoyl)ethyl)thio)benzyl)thio)propionic acid |
| 3-{[(R)-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}{[3-(dimethylamino)-3-oxopropyl]sulfanyl}methyl]sulfanyl}propanoic acid |
| MK-0679 |
| VERLUKAST |
