CAS 122799-38-6|2'-Fluorothymidine

Introduction:Basic information about CAS 122799-38-6|2'-Fluorothymidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2'-Fluorothymidine
CAS Number122799-38-6Molecular Weight260.219
Density1.6±0.1 g/cm3Boiling Point/
Molecular FormulaC10H13FN2O5Melting Point/
MSDS/Flash Point/

Names

Name2'-deoxy-2'-fluorothymidine
SynonymMore Synonyms

2'-Fluorothymidine BiologicalActivity

Description2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine), a bioisostere of both thymidine (TdR) and methyluridine, is a putative highly selective substrate for thymidine kinase type 2 (TK2)[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Wiebe LI, et al. Biochemistry and biology of 2'-Fluoro-2'-deoxythymidine (FT), a putative highly selective substrate for thymidine kinase type 2 (TK2). Curr Radiopharm. 2012 Jan;5(1):38-46.

Chemical & Physical Properties

Density1.6±0.1 g/cm3
Molecular FormulaC10H13FN2O5
Molecular Weight260.219
Exact Mass260.080841
PSA104.55000
LogP-0.72
Index of Refraction1.593
InChIKeyGBBJCSTXCAQSSJ-JXOAFFINSA-N
SMILESCc1cn(C2OC(CO)C(O)C2F)c(=O)[nH]c1=O

Synonyms

2'-fluoro-5-methyl-2'-deoxy-uridine
MFCD03788702
Thymidine, 2'-fluoro-
2'-Fluorothymidine
2'-deoxy-2'-fluorouridine
2'-Fluor-thymidin
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