Introduction:Basic information about CAS 123632-39-3|Fluo-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fluo-3 |
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| CAS Number | 123632-39-3 | Molecular Weight | 769.54 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 1056.0±65.0 °C at 760 mmHg |
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| Molecular Formula | C36H30Cl2N2O13 | Melting Point | >250°C (lit.) |
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| MSDS | USA | Flash Point | 592.4±34.3 °C |
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Names
| Name | Fluo-3 |
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| Synonym | More Synonyms |
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Fluo-3 BiologicalActivity
| Description | Fluo-3 and related molecule Fluo3/AM are used as a fluorescence indicator of intracellular calcium (Ca2+). Fluo-3 may be use for flow cytometry and confocal laser scanning microscopy using visible light excitation (compatible with argon laser sources operating at 488 nm). Fluorescence intensity increases about 40-fold after calcium binding. |
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| Related Catalog | Research Areas >>Others |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 1056.0±65.0 °C at 760 mmHg |
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| Melting Point | >250°C (lit.) |
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| Molecular Formula | C36H30Cl2N2O13 |
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| Molecular Weight | 769.54 |
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| Flash Point | 592.4±34.3 °C |
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| Exact Mass | 768.112488 |
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| PSA | 224.58000 |
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| LogP | 3.25 |
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| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
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| Index of Refraction | 1.734 |
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| InChIKey | OZLGRUXZXMRXGP-UHFFFAOYSA-N |
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| SMILES | Cc1ccc(N(CC(=O)O)CC(=O)O)c(OCCOc2cc(-c3c4cc(Cl)c(=O)cc-4oc4cc(O)c(Cl)cc34)ccc2N(CC(=O)O)CC(=O)O)c1 |
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| Storage condition | 20°C |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Articles222
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| The histidine-rich calcium binding protein (HRC) promotes tumor metastasis in hepatocellular carcinoma and is upregulated by SATB1. Oncotarget 6(9) , 6811-24, (2015) The histidine-rich calcium binding protein (HRC) is a regulator of Ca2+-homeostasis. Herein, we found that HRC was frequently upregulated in human hepatocellular carcinoma (HCC) tissues, and its expre... | |
| mGluR5 in the nucleus accumbens shell regulates morphine-associated contextual memory through reactive oxygen species signaling. Addict. Biol. 20 , 927-40, (2015) Emerging evidence indicates that metabotropic glutamate receptor 5 (mGluR5) critically modulates drug and drug-related behaviors. However, the role of mGluR5 in the opiate-induced contextual memory re... | |
| Involvement of opsins in mammalian sperm thermotaxis. Sci. Rep. 5 , 16146, (2015) A unique characteristic of mammalian sperm thermotaxis is extreme temperature sensitivity, manifested by the capacity of spermatozoa to respond to temperature changes of <0.0006 °C as they swim their ... | |
Synonyms
| fluo 3 |
| {[2-(2-{2-[Bis(carboxymethyl)amino]-5-(2,7-dichloro-6-hydroxy-3-oxo-3H-xanthen-9-yl)phenoxy}ethoxy)-4-methylphenyl](carboxymethyl)amino}acetic acid |