Introduction：Basic information about CAS 38215-36-0|Coumarin VI, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Coumarin VI |
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| CAS Number | 38215-36-0 | Molecular Weight | 350.43400 |
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| Density | 1.311 g/cm3 | Boiling Point | 570.1ºC at 760 mmHg |
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| Molecular Formula | C20H18N2O2S | Melting Point | 208-210 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 298.6ºC |
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Names
| Name | coumarin 6 |
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| Synonym | More Synonyms |
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Coumarin VI BiologicalActivity
| Description | Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Elizebeth Purr, et al. Preparation of PLGA Nanoparticles Encapsulated with Fluorescent Probe Coumarin-6. bioRxiv preprint first posted online Apr. 23, 2019. |
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Chemical & Physical Properties
| Density | 1.311 g/cm3 |
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| Boiling Point | 570.1ºC at 760 mmHg |
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| Melting Point | 208-210 °C(lit.) |
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| Molecular Formula | C20H18N2O2S |
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| Molecular Weight | 350.43400 |
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| Flash Point | 298.6ºC |
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| Exact Mass | 350.10900 |
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| PSA | 74.58000 |
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| LogP | 4.91590 |
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| Index of Refraction | 1.69 |
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| InChIKey | VBVAVBCYMYWNOU-UHFFFAOYSA-N |
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| SMILES | CCN(CC)c1ccc2cc(-c3nc4ccccc4s3)c(=O)oc2c1 |
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| Stability | Stable. Incompatible with strong oxidizing agents. |
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| Water Solubility | NEGLIGIBLE |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xn: Harmful; |
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| Risk Phrases | R20/21/22;R36/37/38 |
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| Safety Phrases | S22-S24/25-S37/39-S26 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| HS Code | 2934999090 |
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Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Articles26
More Articles
| Herceptin conjugated PLGA-PHis-PEG pH sensitive nanoparticles for targeted and controlled drug delivery. Int. J. Pharm. 487 , 81-90, (2015) A dual functional nano-scaled drug carrier, comprising of a targeting ligand and pH sensitivity, has been made in order to increase the specificity and efficacy of the drug delivery system. The nanopa... | |
| Positive-charged solid lipid nanoparticles as paclitaxel drug delivery system in glioblastoma treatment. Eur. J. Pharm. Biopharm. 88(3) , 746-58, (2015) Paclitaxel loaded solid lipid nanoparticles (SLN) of behenic acid were prepared with the coacervation technique. Generally, spherical shaped SLN with mean diameters in the range 300–600 nm were obtain... | |
| Bioactive Hybrid Particles from Poly(D,L-lactide-co-glycolide) Nanoparticle Stabilized Lipid Droplets. ACS Appl. Mater. Interfaces 7 , 17460-70, (2015) Biodegradable and bioactive hybrid particles composed of poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles and medium-chain triglycerides were prepared by spray drying lipid-in-water emulsions stabi... | |
Synonyms
| Coumarin 6,laser grade |
| EINECS 253-830-2 |
| 3-(2-Benzothiazolyl)-N,N-diethylumbelliferylamine (3-(2-Benzothiazolyl)-7-(diethylamino)coumarin |
| coumarin-540 |
| 3-(1,3-benzothiazol-2-yl)-7-(diethylamino)chromen-2-one |
| 3-(benzo[d]thiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one |
| MFCD00041869 |
| 3-(2-Benzothiazolyl)-7-(diethylamino)coumarin |
| 3-(2-benzothiazolyl)-7-(diethylamino)-2H-1-benzopyran-2-one |
| 3-benzothiazol-2-yl-7-(diethylamino)chromen-2-one |
| 3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one |
| 3-(Benzothiazo-2-yl)-7-(diethylamino)-2H-chromen-2-one |
| 2H-1-Benzopyran-2-one,3-(2-benzothiazolyl)-7-(diethylamino) |
