CAS 95399-71-6|Fosinoprilat

Introduction：Basic information about CAS 95399-71-6|Fosinoprilat, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Fosinoprilat BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Fosinoprilat
CAS Number	95399-71-6	Molecular Weight	435.49400
Density	1.238g/cm3	Boiling Point	728.9ºC at 760mmHg
Molecular Formula	C₂₃H₃₄NO₅P	Melting Point	>300ºC
MSDS	/	Flash Point	394.6ºC

Names

Name	fosinoprilat
Synonym	More Synonyms

Fosinoprilat BiologicalActivity

Description	Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Fosfenopril alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes[1][2].
Related Catalog	Signaling Pathways >>Immunology/Inflammation >>Toll-like Receptor (TLR)Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Metabolic Enzyme/Protease >>Angiotensin-converting Enzyme (ACE)Research Areas >>Inflammation/Immunology
Target	TLR4 NF-κB
References	[1]. Yang S, et al. Fosinoprilat alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes. Cell Immunol. 2013 Jul-Aug;284(1-2):182-6. [2]. DeForrest JM, et al. Fosinopril, a phosphinic acid inhibitor of angiotensin I converting enzyme: in vitro and preclinical in vivo pharmacology. J Cardiovasc Pharmacol. 1989 Nov;14(5):730-6.

Chemical & Physical Properties

Density	1.238g/cm3
Boiling Point	728.9ºC at 760mmHg
Melting Point	>300ºC
Molecular Formula	C₂₃H₃₄NO₅P
Molecular Weight	435.49400
Flash Point	394.6ºC
Exact Mass	435.21700
PSA	104.72000
LogP	4.09960
Index of Refraction	1.564
InChIKey	WOIWWYDXDVSWAZ-RTWAWAEBSA-N
SMILES	O=C(O)C1CC(C2CCCCC2)CN1C(=O)CP(=O)(O)CCCCc1ccccc1

Safety Information

RIDADR	NONH for all modes of transport

Synonyms

forsythiaside

forsytoside A

forsythoside

FOSINOPRILAT

Forsythiaside A

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