Introduction：Basic information about CAS 439574-61-5|ITK inhibitor, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | ITK inhibitor |
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| CAS Number | 439574-61-5 | Molecular Weight | 609.802 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C31H39N5O4S2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | N-[5-[5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl]sulfanyl-1,3-thiazol-2-yl]-4-[(3-methylbutan-2-ylamino)methyl]benzamide |
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| Synonym | More Synonyms |
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ITK inhibitor BiologicalActivity
| Description | ITK inhibitor is a potent ITK inhibitor. |
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| Related Catalog | Signaling Pathways >>Protein Tyrosine Kinase/RTK >>ItkResearch Areas >>Inflammation/Immunology |
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| References | [1]. Barrish, Joel C.; Das, Jagabandhu; Kanner, Steven B.; Liu, Chunjian; Spergel, Steven H.; Witayk, John; Doweyko, Arthur M. P.; Furch, Joseph A. Preparation of thiazolyl inhibitors of Tec family tyrosine kinases. PCT Int. Appl.(2002),149 pp. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Molecular Formula | C31H39N5O4S2 |
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| Molecular Weight | 609.802 |
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| Exact Mass | 609.244324 |
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| PSA | 157.41000 |
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| LogP | 4.20 |
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| Index of Refraction | 1.640 |
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| InChIKey | RRHONYZEMUNMJX-UHFFFAOYSA-N |
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| SMILES | COc1cc(C)c(Sc2cnc(NC(=O)c3ccc(CNC(C)C(C)C)cc3)s2)cc1C(=O)N1CCN(C(C)=O)CC1 |
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Synonyms
| ITK inhibitor |
| HMS3265G21 |
| HMS3265G22 |
| HMS3265H21 |
| Benzamide, N-[5-[[5-[(4-acetyl-1-piperazinyl)carbonyl]-4-methoxy-2-methylphenyl]thio]-2-thiazolyl]-4-[[(1,2-dimethylpropyl)amino]methyl]- |
| HMS3265H22 |
| N-[5-({5-[(4-Acetyl-1-piperazinyl)carbonyl]-4-methoxy-2-methylphenyl}sulfanyl)-1,3-thiazol-2-yl]-4-{[(3-methyl-2-butanyl)amino]methyl}benzamide |
