CAS 192203-60-4|Carboxypeptidase G2 (CPG2) Inhibitor

Introduction：Basic information about CAS 192203-60-4|Carboxypeptidase G2 (CPG2) Inhibitor, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Carboxypeptidase G2 (CPG2) Inhibitor BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Carboxypeptidase G2 (CPG2) Inhibitor
CAS Number	192203-60-4	Molecular Weight	313.32600
Density	1.43	Boiling Point	/
Molecular Formula	C₁₃H₁₅NO₆S	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	(2S)-2-[(4-methoxyphenyl)sulfanylcarbonylamino]pentanedioic acid
Synonym	More Synonyms

Carboxypeptidase G2 (CPG2) Inhibitor BiologicalActivity

Description	Carboxypeptidase G2 (CPG2) Inhibitor is a novel Carboxypeptidase G2 (CPG2) Inhibitor, Antitumor agents.
Related Catalog	Signaling Pathways >>Metabolic Enzyme/Protease >>CarboxypeptidaseResearch Areas >>Cancer
References	[1]. Khan, Tariq H.; Eno-Amooquaye, Ebun A.; Searle, Frances et al. Novel Inhibitors of Carboxypeptidase G2 (CPG2): Potential Use in Antibody-Directed Enzyme Prodrug Therapy. Journal of Medicinal Chemistry (1999), 42(6), 951-956. [2]. Friedlos F, Lehouritis P, Ogilvie L et al. Attenuated Salmonella targets prodrug activating enzyme carboxypeptidase G2 to mouse melanoma and human breast and colon carcinomas for effective suicide gene therapy. Clin Cancer Res. 2008 Jul 1;14(13):4259-66. [3]. Schepelmann S, Ogilvie LM, Hedley D et al. Suicide gene therapy of human colon carcinoma xenografts using an armed oncolytic adenovirus expressing carboxypeptidase G2. Cancer Res. 2007 May 15;67(10):4949-55. [4]. Schepelmann S, Hallenbeck P, Ogilvie LM et al. Systemic gene-directed enzyme prodrug therapy of hepatocellular carcinoma using a targeted adenovirus armed with carboxypeptidase G2. Cancer Res. 2005 Jun 15;65(12):5003-8.

Description

Carboxypeptidase G2 (CPG2) Inhibitor is a novel Carboxypeptidase G2 (CPG2) Inhibitor, Antitumor agents.

Related Catalog

Signaling Pathways >>Metabolic Enzyme/Protease >>CarboxypeptidaseResearch Areas >>Cancer

References

[1]. Khan, Tariq H.; Eno-Amooquaye, Ebun A.; Searle, Frances et al. Novel Inhibitors of Carboxypeptidase G2 (CPG2): Potential Use in Antibody-Directed Enzyme Prodrug Therapy. Journal of Medicinal Chemistry (1999), 42(6), 951-956.

[2]. Friedlos F, Lehouritis P, Ogilvie L et al. Attenuated Salmonella targets prodrug activating enzyme carboxypeptidase G2 to mouse melanoma and human breast and colon carcinomas for effective suicide gene therapy. Clin Cancer Res. 2008 Jul 1;14(13):4259-66.

[3]. Schepelmann S, Ogilvie LM, Hedley D et al. Suicide gene therapy of human colon carcinoma xenografts using an armed oncolytic adenovirus expressing carboxypeptidase G2. Cancer Res. 2007 May 15;67(10):4949-55.

[4]. Schepelmann S, Hallenbeck P, Ogilvie LM et al. Systemic gene-directed enzyme prodrug therapy of hepatocellular carcinoma using a targeted adenovirus armed with carboxypeptidase G2. Cancer Res. 2005 Jun 15;65(12):5003-8.

Chemical & Physical Properties

Density	1.43
Molecular Formula	C₁₃H₁₅NO₆S
Molecular Weight	313.32600
Exact Mass	313.06200
PSA	141.72000
LogP	2.01930
InChIKey	OBCGYIKABKFIQB-JTQLQIEISA-N
SMILES	COc1ccc(SC(=O)NC(CCC(=O)O)C(=O)O)cc1

Synonyms

CS-0824

Carboxypeptidase G2 (CPG2) Inhibitor

L-Glutamic acid,N-[[(4-methoxyphenyl)thio]carbonyl]

Carboxypeptidase G2 (CPG2) Inhibitor||L-Glutamic acid,N-[[(4-methoxyphenyl)thio]carbonyl]

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