Introduction：Basic information about CAS 99694-90-3|Scholaricine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Scholaricine |
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| CAS Number | 99694-90-3 | Molecular Weight | 356.42 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 519.5±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H24N2O4 | Melting Point | / |
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| MSDS | / | Flash Point | 268.0±30.1 °C |
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Names
| Name | Methyl (19S)-12,19-dihydroxy-2,16-didehydrocuran-17-oate |
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| Synonym | More Synonyms |
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Scholaricine BiologicalActivity
| Description | Scholaricine (compound 13 ) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC50 value of 13.35 μM[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Shin-Jowl Tan , et al. Strychnan and secoangustilobine A type alkaloids from Alstonia spatulata. Revision of the C-20 configuration of scholaricine. J Nat Prod. 2010, 73, 11. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 519.5±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H24N2O4 |
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| Molecular Weight | 356.42 |
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| Flash Point | 268.0±30.1 °C |
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| Exact Mass | 356.173615 |
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| PSA | 82.03000 |
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| LogP | 1.41 |
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| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
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| Index of Refraction | 1.684 |
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| InChIKey | GNCUCBQZLQLSOF-UQXFTUDMSA-N |
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| SMILES | COC(=O)C1=C2Nc3c(O)cccc3C23CCN2CC(C(C)O)C1CC23 |
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Safety Information
Synonyms
| Curan-17-oic acid, 2,16-didehydro-12,19-dihydroxy-, methyl ester, (19S)- |
| Methyl (19S)-12,19-dihydroxy-2,16-didehydrocuran-17-oate |
