Introduction：Basic information about CAS 146672-02-8|4-Hydroxybenzoic acid-13c, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Hydroxybenzoic acid-13c |
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| CAS Number | 146672-02-8 | Molecular Weight | 139.11300 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C7H6O3 | Melting Point | 214-215ºC(lit.) |
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| MSDS | USA | Flash Point | / |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | 4-hydroxybenzoic acid |
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| Synonym | More Synonyms |
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4-Hydroxybenzoic acid-13c BiologicalActivity
| Description | 4-Hydroxybenzoic acid-13C is the 13C labeled 4-Hydroxybenzoic acid[1]. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL[2]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
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| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Cho JY, Antimicrobial activity of 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid isolated and identified from rice hull. Biosci Biotechnol Biochem. 1998 Nov;62(11):2273-6. |
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Chemical & Physical Properties
| Melting Point | 214-215ºC(lit.) |
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| Molecular Formula | C7H6O3 |
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| Molecular Weight | 139.11300 |
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| Exact Mass | 139.03500 |
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| PSA | 57.53000 |
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| LogP | 1.09040 |
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| InChIKey | FJKROLUGYXJWQN-CDYZYAPPSA-N |
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| SMILES | O=C(O)c1ccc(O)cc1 |
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H315-H319-H335 |
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| Precautionary Statements | P261-P305 + P351 + P338 |
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| Hazard Codes | Xi |
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| RIDADR | NONH for all modes of transport |
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Synonyms
| 4-Hydroxybenzoic acid-|A-13C |
