CAS 579-21-5|Lobelanine

Introduction：Basic information about CAS 579-21-5|Lobelanine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Lobelanine BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Lobelanine
CAS Number	579-21-5	Molecular Weight	335.43900
Density	1.076g/cm3	Boiling Point	476.4ºC at 760mmHg
Molecular Formula	C₂₂H₂₅NO₂	Melting Point	99°
MSDS	/	Flash Point	196.2ºC

Names

Name	2-[(2R,6S)-1-methyl-6-phenacylpiperidin-2-yl]-1-phenylethanone
Synonym	More Synonyms

Lobelanine BiologicalActivity

Description	Lobelanine (8,10-Diphenyllobelidione) is a chemical precursor for the biosynthesis of Lobeline. Lobeline is a partial nicotinic agonist and is used as a smoking cessation agent[1][2].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Guangrong Zheng, Peter A. Crooks. (2015) ChemInform Abstract: Synthesis of Lobeline, Lobelane and Their Analogues. A Review. ChemInform 46:42, pages no-no. [2]. Stead LF, et al. Lobeline for smoking cessation. Cochrane Database Syst Rev. 2012;2012(2):CD000124. Published 2012 Feb 15.

Description

Lobelanine (8,10-Diphenyllobelidione) is a chemical precursor for the biosynthesis of Lobeline. Lobeline is a partial nicotinic agonist and is used as a smoking cessation agent[1][2].

Related Catalog

Research Areas >>OthersSignaling Pathways >>Others >>Others

References

[1]. Guangrong Zheng, Peter A. Crooks. (2015) ChemInform Abstract: Synthesis of Lobeline, Lobelane and Their Analogues. A Review. ChemInform 46:42, pages no-no.

[2]. Stead LF, et al. Lobeline for smoking cessation. Cochrane Database Syst Rev. 2012;2012(2):CD000124. Published 2012 Feb 15.

Chemical & Physical Properties

Density	1.076g/cm3
Boiling Point	476.4ºC at 760mmHg
Melting Point	99°
Molecular Formula	C₂₂H₂₅NO₂
Molecular Weight	335.43900
Flash Point	196.2ºC
Exact Mass	335.18900
PSA	37.38000
LogP	4.32320
Index of Refraction	1.554
InChIKey	IDEMKXUAULKYJV-BGYRXZFFSA-N
SMILES	CN1C(CC(=O)c2ccccc2)CCCC1CC(=O)c1ccccc1
Storage condition	2-8°C

Safety Information

RIDADR	UN 1544
Packaging Group	III
Hazard Class	6.1(b)

Synonyms

Lobelanine

1-Methyl-2r,6c-diphenacyl-piperidin

cis-2,2'-(1-methyl-2,6-piperidinediyl)bis[1-phenyl-ethanone]

1-methyl-2r,6c-diphenacyl-piperidine

Ethanone,2,2'-(1-methyl-2,6-piperidinediyl)bis(1-phenyl-,cis

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