Introduction：Basic information about CAS 1185166-01-1|Metformin D6 hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Metformin D6 hydrochloride |
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| CAS Number | 1185166-01-1 | Molecular Weight | 171.662 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C4H6D6ClN5 | Melting Point | 215-218°C |
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| MSDS | ChineseUSA | Flash Point | / |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | 3-(diaminomethylidene)-1,1-bis(trideuteriomethyl)guanidine,hydrochloride |
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| Synonym | More Synonyms |
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Metformin D6 hydrochloride BiologicalActivity
| Description | Metformin D6 hydrochloride is a deuterium labeled Metformin hydrochloride. Metformin hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy[1]. |
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| Related Catalog | Signaling Pathways >>Epigenetics >>AMPKResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>Autophagy >>AutophagySignaling Pathways >>PI3K/Akt/mTOR >>AMPKSignaling Pathways >>Autophagy >>MitophagyResearch Areas >>Metabolic Disease |
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| Target | AMPK |
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| References | [1]. Soraya H, et al. Acute treatment with metformin improves cardiac function following NSC 37745 induced myocardial infarction in rats. Pharmacol Rep. 2012;64(6):1476-84. |
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Chemical & Physical Properties
| Melting Point | 215-218°C |
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| Molecular Formula | C4H6D6ClN5 |
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| Molecular Weight | 171.662 |
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| Exact Mass | 171.115784 |
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| PSA | 88.99000 |
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| LogP | 1.05850 |
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| InChIKey | OETHQSJEHLVLGH-TXHXQZCNSA-N |
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| SMILES | CN(C)C(=N)N=C(N)N.Cl |
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| Storage condition | -20°C Freezer |
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H302-H315-H319 |
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| Precautionary Statements | P305 + P351 + P338 |
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| Hazard Codes | Xn |
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| Risk Phrases | 22-36/38 |
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| Safety Phrases | 26 |
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| RIDADR | NONH for all modes of transport |
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Synonyms
| Metformin-(dimethyl-d6) hydrochloride |
| N,N-Bis[(H)methyl]imidodicarbonimidic diamide hydrochloride (1:1) |
| Imidodicarbonimidic diamide, N,N-dimethyl-d-, hydrochloride (1:1) |
| Diabex-d6,Glucophage-d6 |
| Diabetosan-d6 |
| Metformin-d6,Hydrochloride |
| N,N-Dimethylimidodicarbonimidic Diamide-d6,Hydrochloride |
| Metiguanide-d6 |
