CAS 1204707-71-0|SRT3109

Introduction：Basic information about CAS 1204707-71-0|SRT3109, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. SRT3109 BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	SRT3109
CAS Number	1204707-71-0	Molecular Weight	475.533
Density	1.6±0.1 g/cm3	Boiling Point	726.6±70.0 °C at 760 mmHg
Molecular Formula	C₁₈H₂₃F₂N₅O₄S₂	Melting Point	/
MSDS	/	Flash Point	393.3±35.7 °C

Names

Name	N-[2-[(2,3-difluorophenyl)methylsulfanyl]-6-[[(2R,3R)-3,4-dihydroxybutan-2-yl]amino]pyrimidin-4-yl]azetidine-1-sulfonamide
Synonym	More Synonyms

SRT3109 BiologicalActivity

Description	SRT3109 is an antagonist of CXCR2, with a pIC50 of 8.2, and used in the research of chemokine mediated diseases.
Related Catalog	Research Areas >>Inflammation/Immunology
Target	CXCR2:8.2 (pIC50)
In Vitro	SRT3109 (Example 1) is an antagonist of CXCR2, with a pIC50 of 8.2, and used in the research of chemokine mediated diseases[1].
References	[1]. Premji Meghani, et al. Pyrimidyl sulfonaminde derivative and its use for the treatment of chemokine mediated diseases. WO2010007427A1

Chemical & Physical Properties

Density	1.6±0.1 g/cm3
Boiling Point	726.6±70.0 °C at 760 mmHg
Molecular Formula	C₁₈H₂₃F₂N₅O₄S₂
Molecular Weight	475.533
Flash Point	393.3±35.7 °C
Exact Mass	475.115936
PSA	161.36000
LogP	2.07
Vapour Pressure	0.0±2.5 mmHg at 25°C
Index of Refraction	1.661
InChIKey	QVKPEMXUBULFBM-RISCZKNCSA-N
SMILES	CC(Nc1cc(NS(=O)(=O)N2CCC2)nc(SCc2cccc(F)c2F)n1)C(O)CO
Storage condition	2-8℃

Synonyms

Y0301

CS-0977

1-Azetidinesulfonamide, N-[2-[[(2,3-difluorophenyl)methyl]thio]-6-[[(1R,2R)-2,3-dihydroxy-1-methylpropyl]amino]-4-pyrimidinyl]-

SRT-3109

cc-200

N-(2-[(2,3-Difluorobenzyl)sulfanyl]-6-{[(2R,3R)-3,4-dihydroxy-2-butanyl]amino}-4-pyrimidinyl)-1-azetidinesulfonamide

SRT3109

Recommended......