CAS 19202-36-9|hinokiflavone

Introduction：Basic information about CAS 19202-36-9|hinokiflavone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namehinokiflavone
CAS Number19202-36-9Molecular Weight538.458
Density1.6±0.1 g/cm3Boiling Point841.5±65.0 °C at 760 mmHg
Molecular FormulaC30H18O10Melting Point353-355ºC
MSDS/Flash Point284.8±27.8 °C

Names

Namehinokiflavone
SynonymMore Synonyms

hinokiflavone BiologicalActivity

DescriptionHinokiflavone is a novel modulator of pre-mRNA splicing activity in vitro and in cellulo. Hinokiflavone blocks splicing of pre-mRNA substrates by inhibiting spliceosome assembly, specifically preventing B complex formation. Hinokiflavone is a SUMO protease inhibitor, inhibiting sentrin-specific protease 1 (SENP1) activity[1].
Related CatalogResearch Areas >>Others
References

[1]. Pawellek A, et al. Characterisation of the biflavonoid hinokiflavone as a pre-mRNA splicing modulator that inhibits SENP. Elife. 2017 Sep 8;6. pii: e27402.

Chemical & Physical Properties

Density1.6±0.1 g/cm3
Boiling Point841.5±65.0 °C at 760 mmHg
Melting Point353-355ºC
Molecular FormulaC30H18O10
Molecular Weight538.458
Flash Point284.8±27.8 °C
Exact Mass538.090027
PSA170.80000
LogP4.33
Vapour Pressure0.0±3.2 mmHg at 25°C
Index of Refraction1.771
InChIKeyWTDHMFBJQJSTMH-UHFFFAOYSA-N
SMILESO=c1cc(-c2ccc(Oc3c(O)cc4oc(-c5ccc(O)cc5)cc(=O)c4c3O)cc2)oc2cc(O)cc(O)c12
Storage condition2-8℃

Safety Information

Hazard CodesXi

Synonyms

6-[4-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)phenoxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
hynokiflavone
hinokiflavone
4H-1-Benzopyran-4-one, 6-(4-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)phenoxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-
4',6''-O-Biapigenin
6-[4-(5,7-dihydroxy-4-oxochromen-2-yl)phenoxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
6-(4-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)phenoxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone
4',6"-O-Biapigenin
4H-1-Benzopyran-4-one, 6-[4-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)phenoxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-
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