CAS 73168-24-8|(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin trifluoroacetate salt

Introduction：Basic information about CAS 73168-24-8|(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles34
6. Synonyms

Common Name	(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin trifluoroacetate salt
CAS Number	73168-24-8	Molecular Weight	1151.36
Density	1.5 g/cm3	Boiling Point	/
Molecular Formula	C₅₂H₇₄N₁₄O₁₂S₂	Melting Point	/
MSDS	ChineseUSA	Flash Point	/
Symbol	GHS07	Signal Word	Warning

Names

Name	3-mercapto-3-methyl-butyryl-tyr(me)-phe-gln-asn-cys-pro-arg-gly-nh2
Synonym	More Synonyms

BiologicalActivity

Description	(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin (SKF 100273) is a vasopressin V1 receptor selective antagonist[1].
Related Catalog	Signaling Pathways >>GPCR/G Protein >>Vasopressin ReceptorResearch Areas >>Metabolic Disease
References	[1]. Arai Y, et al. New topics in vasopressin receptors and approach to novel drugs: research and development of conivaptan hydrochloride (YM087), a drug for the treatment of hyponatremia. J Pharmacol Sci. 2009 Jan;109(1):53-9.

Chemical & Physical Properties

Density	1.5 g/cm3
Molecular Formula	C₅₂H₇₄N₁₄O₁₂S₂
Molecular Weight	1151.36
Exact Mass	1150.51000
PSA	475.01000
LogP	3.52940
Index of Refraction	1.695
InChIKey	QVQOGNOOAMQKCE-ZTYVOHGWSA-N
SMILES	COc1ccc(CC2NC(=O)CC3(CCCCC3)SSCC(C(=O)N3CCCC3C(=O)NC(CCCN=C(N)N)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(Cc3ccccc3)NC2=O)cc1

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H332
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R20
Safety Phrases	36
RIDADR	NONH for all modes of transport

Articles34

Peripheral mechanisms involved in the pressor and bradycardic effects of centrally administered arachidonic acid

Prostaglandins Leukot. Essent. Fatty Acids 78(6) , 361-8, (2008)

In the current study, we aimed to determine the cardiovascular effects of arachidonic acid and peripheral mechanisms mediated these effects in normotensive conscious rats. Studies were performed in ma...

Contractile responses of human thyroid arteries to vasopressin.

Life Sci. 93(15) , 525-9, (2013)

In the present study we investigated the intervention of nitric oxide and prostacyclin in the responses to vasopressin of isolated thyroid arteries obtained from multi-organ donors.Paired artery rings...

Selective blockade of oxytocin and vasopressin V(1a) receptors in anaesthetised rats: evidence that activation of oxytocin receptors rather than V(1a) receptors increases sodium excretion.

Nephron. Exp. Nephrol. 117(3) , p21-6, (2011)

Although it is known that moderate-to-high doses of the neurohypophysial hormones oxytocin and vasopressin are natriuretic, doubts remain over the identity of the receptors responsible. To address thi...

Synonyms

Avpa

Aavp

MANNING COMPOUND

AVPX

Recommended......