CAS 121545-65-1|Protein Kinase C (19-31)

Introduction：Basic information about CAS 121545-65-1|Protein Kinase C (19-31), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Protein Kinase C (19-31) BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Protein Kinase C (19-31)
CAS Number	121545-65-1	Molecular Weight	1543.82
Density	/	Boiling Point	/
Molecular Formula	C₆₇H₁₁₈N₂₆O₁₆	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	protein kinase c (19-31)
Synonym	More Synonyms

Protein Kinase C (19-31) BiologicalActivity

Description	Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate peptide for testing the protein kinase C activity. Protein kinase C (PKC) is involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins[1][2].
Related Catalog	Signaling Pathways >>Epigenetics >>PKCResearch Areas >>OthersSignaling Pathways >>TGF-beta/Smad >>PKC
References	[1]. Mellor H, et al. The extended protein kinase C superfamily. Biochem J. 1998 Jun 1;332 ( Pt 2):281-92. [2]. Nishizuka Y (1995). Protein kinase C and lipid signaling for sustained cellular responses" (abstract). FASEB J. 9 (7): 484–96.

Description

Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate peptide for testing the protein kinase C activity. Protein kinase C (PKC) is involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins[1][2].

Related Catalog

Signaling Pathways >>Epigenetics >>PKCResearch Areas >>OthersSignaling Pathways >>TGF-beta/Smad >>PKC

References

[1]. Mellor H, et al. The extended protein kinase C superfamily. Biochem J. 1998 Jun 1;332 ( Pt 2):281-92.

[2]. Nishizuka Y (1995). Protein kinase C and lipid signaling for sustained cellular responses" (abstract). FASEB J. 9 (7): 484–96.

Chemical & Physical Properties

Molecular Formula	C₆₇H₁₁₈N₂₆O₁₆
Molecular Weight	1543.82
Exact Mass	1542.92000
PSA	736.44000
LogP	3.78570
InChIKey	OLYXRRDLXDCSNP-UHFFFAOYSA-N
SMILES	CC(C)CC(NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C(C)NC(=O)C(Cc1ccccc1)NC(=O)C(N)CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCC(N)=O)C(=O)NC(CCCCN)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)O)C(C)C

Synonyms

rfarkgalrqknv

protein kinase c fragment 19-31 amide

arg-phe-ala-arg-lys-gly-ala-leu-arg-gln-lys-asn-val-nh2

pkc inhibitor peptide

protein kinase c inhibitor peptide 19-31

h-arg-phe-ala-arg-lys-gly-ala-leu-arg-gln-lys-asn-val-oh

arg-phe-ala-arg-lys-gly-ala-leu-arg-gln-lys-asn-val

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