CAS 70967-97-4|Suc-Ala-Ala-Pro-Phe-pNA
| Common Name | Suc-Ala-Ala-Pro-Phe-pNA | ||
|---|---|---|---|
| CAS Number | 70967-97-4 | Molecular Weight | 624.642 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 1072.8±65.0 °C at 760 mmHg |
| Molecular Formula | C30H36N6O9 | Melting Point | / |
| MSDS | USA | Flash Point | 602.6±34.3 °C |
Names
| Name | suc-ala-ala-pro-phe-pna |
|---|---|
| Synonym | More Synonyms |
Suc-Ala-Ala-Pro-Phe-pNA BiologicalActivity
| Description | Suc-AAPF-pNA (Suc-Ala-Ala-Pro-Phe-pNA) is a chromogenic p-nitroanilide (pNA) substrate with the Km of 1.7 mM. Suc-AAPF-pNA can be used for the Measurement of free and membrane-bound cathepsin G in human neutrophils[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
| References | [1]. Sylvie Attucci, et al. Measurement of free and membrane-bound cathepsin G in human neutrophils using new sensitive fluorogenic substrates. Biochem J. 2002 Sep 15;366(Pt 3):965-70. |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 1072.8±65.0 °C at 760 mmHg |
| Molecular Formula | C30H36N6O9 |
| Molecular Weight | 624.642 |
| Flash Point | 602.6±34.3 °C |
| Exact Mass | 624.254395 |
| PSA | 219.83000 |
| LogP | 2.58 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.614 |
| Storage condition | −20°C |
| Water Solubility | DMF: 25 mg/mL, clear, light yellow |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles8
More Articles| Suppression of problematic compound oligomerization by cosolubilization of nondetergent sulfobetaines. ChemMedChem 10(4) , 736-41, (2015) Numerous small organic compounds exist in equilibrium among monomers, soluble oligomers, and insoluble aggregates in aqueous solution. Compound aggregation is a major reason for false positives in dru... | |
| Covalent Incorporation of Trehalose within Hydrogels for Enhanced Long-Term Functional Stability and Controlled Release of Biomacromolecules. Adv. Healthc. Mater. 4 , 1802-12, (2015) Hydrogels with covalently incorporated trehalose are synthesized using thiol-ene Michael addition. Trehalose hydrogels afford prolonged stabilization and -controlled release of model enzymes in vitro ... | |
| Evidence of multiple/cross resistance to Bt and organophosphate insecticides in Puerto Rico population of the fall armyworm, Spodoptera frugiperda. Pestic. Biochem. Physiol. 122 , 15-21, (2015) Fall armyworm (FAW) is a damaging pest of many economic crops. Long-term use of chemical control prompted resistance development to many insecticide classes. Many populations were found to be signific... |
Synonyms
| SUC-ALA-ALA-PRO-PHE-PARANITROANILIDE |
| N-SUCCINYL-ALA-ALA-PRO-PHE P-NITROANILIDE |
| Cathepsin G Substrate I |
| CATHEPSIN G SUBSTRATE I,COLORIMETRIC |
| SAAPNA |
| SUC-AAPF-PNA |
| N-SUCCINYL-ALA-ALA-PRO-PHE-PNA |
| SUCCINYL-ALA-ALA-PRO-PHE-P-NITROANILIDE |
| N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine p-nitroanilide |
| N-Succ-Ala-Ala-Pro-Phe-p-nitroanilide |
| L-Phenylalaninamide, N-(3-carboxy-1-oxopropyl)alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)- |
| N-Succinyl-Ala-Ala-Pro-Phe 4-nitroanilide |
| N-(3-Carboxypropanoyl)alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-phenylalaninamide |
| MFCD00077161 |
