CAS 20290-10-2|M-6-G TRIFLUOROACETATE-HYDRATE
| Common Name | M-6-G TRIFLUOROACETATE-HYDRATE | ||
|---|---|---|---|
| CAS Number | 20290-10-2 | Molecular Weight | 461.46200 |
| Density | 1.64g/cm3 | Boiling Point | 731.6ºC at 760mmHg |
| Molecular Formula | C23H27NO9 | Melting Point | 237-240°C (dec.) |
| MSDS | ChineseUSA | Flash Point | 396.3ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | Morphine 6-β-D-Glucuronide |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.64g/cm3 |
|---|---|
| Boiling Point | 731.6ºC at 760mmHg |
| Melting Point | 237-240°C (dec.) |
| Molecular Formula | C23H27NO9 |
| Molecular Weight | 461.46200 |
| Flash Point | 396.3ºC |
| Exact Mass | 461.16900 |
| PSA | 149.15000 |
| Vapour Pressure | 1.8E-22mmHg at 25°C |
| Index of Refraction | 1.731 |
| InChIKey | GNJCUHZOSOYIEC-GAROZEBRSA-N |
| SMILES | CN1CCC23c4c5ccc(O)c4OC2C(OC2OC(C(=O)O)C(O)C(O)C2O)C=CC3C1C5 |
| Storage condition | −20°C |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 432 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 67(4),97P,1971
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H312-H317-H332 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | 20/21/22-43 |
| Safety Phrases | 36 |
| RIDADR | UN 1993C 3 / PGIII |
| WGK Germany | 3 |
| RTECS | LZ6500700 |
Articles32
More Articles| Morphine glucuronidation increases its analgesic effect in guinea pigs. Life Sci. 109(2) , 104-10, (2014) Morphine is extensively metabolized to neurotoxic morphine-3-glucuronide (M3G) and opioid agonist morphine-6-glucuronide (M6G). Due to these different roles, interindividual variability and co-adminis... | |
| [Rapid opiate detoxification under anesthesia (RODA)]. Rev. Med. Liege. 68(5-6) , 298-302, (2013) Rapid Opiate Detoxification under Anesthesia (RODA) involves the use of opiate antagonists combined with anesthesia and pharmacotherapy to reduce withdrawal symptoms. The aim of our study was to measu... | |
| [Blood-brain barrier transport of opioid analgesics]. Yakugaku Zasshi 131(10) , 1445-51, (2011) Opioid analgesics exhibit cationic properties under physiological conditions, and the mechanism underlying permeation of the blood-brain barrier thus cannot be fully explained by simple diffusion alon... |
Synonyms
| Morphine glucuronide |
