CAS 54149-17-6|m-PEG2-Br

Introduction：Basic information about CAS 54149-17-6|m-PEG2-Br, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. m-PEG2-Br BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Articles3
7. Synonyms

Common Name	m-PEG2-Br
CAS Number	54149-17-6	Molecular Weight	183.044
Density	1.3±0.1 g/cm3	Boiling Point	184.4±15.0 °C at 760 mmHg
Molecular Formula	C₅H₁₁BrO₂	Melting Point	/
MSDS	ChineseUSA	Flash Point	73.9±0.0 °C

Names

Name	1-Bromo-2-(2-methoxyethoxy)ethane
Synonym	More Synonyms

m-PEG2-Br BiologicalActivity

Description	m-PEG2-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	184.4±15.0 °C at 760 mmHg
Molecular Formula	C₅H₁₁BrO₂
Molecular Weight	183.044
Flash Point	73.9±0.0 °C
Exact Mass	181.994232
PSA	18.46000
LogP	0.54
Vapour Pressure	1.0±0.3 mmHg at 25°C
Index of Refraction	1.445
InChIKey	HUXJXNSHCKHFIL-UHFFFAOYSA-N
SMILES	COCCOCCBr
Storage condition	Refrigerator (+4°C)

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Risk Phrases	36/37/38
Safety Phrases	S24/25
WGK Germany	3
HS Code	2909199090

Customs

HS Code	2909199090
Summary	2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles3

Noncovalent polycationic coatings for capillaries in capillary electrophoresis of proteins.

Anal. Chem. 69(7) , 1370-9, (1997)

The adsorption of proteins with net positive charges (pI > pH) on the walls of fused-silica capillaries is a common problem in the analysis of proteins by capillary electrophoresis. This paper explore...

Molecular engineering of photoremovable protecting groups for two-photon uncaging.

Angew. Chem. Int. Ed. Engl. 47(49) , 9525-9, (2008)

Effect of charge density on energy-transfer properties of cationic conjugated polymers. Pu K-Y, et al.

Adv. Funct. Mater. 18(8) , 1321-1328

Synonyms

1-Bromo-(2-methoxyethoxy)ethane

1-Bromo-2-(2-methoxyethoxy)ethane

EINECS 259-000-6

MFCD00000238

1-(2-Bromoethoxy)-2-methoxyethane

Ethane, 1-bromo-2-(2-methoxyethoxy)-

Ethane, 1-(2-bromoethoxy)-2-methoxy-

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