Introduction：Basic information about CAS 121058-82-0|N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine |
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| CAS Number | 121058-82-0 | Molecular Weight | 571.62 |
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| Density | 1.32±0.1 g/cm3(Predicted) | Boiling Point | / |
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| Molecular Formula | C32H33N3O7 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.32±0.1 g/cm3(Predicted) |
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| Molecular Formula | C32H33N3O7 |
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| Molecular Weight | 571.62 |
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| Exact Mass | 587.22700 |
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| PSA | 141.37000 |
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| LogP | 2.91980 |
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| InChIKey | AFQGZOMSSIQDMD-PYYPWFDZSA-N |
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| SMILES | COc1ccc(C(OCC2OC(n3ccc(NC(C)=O)nc3=O)C(O)C2O)(c2ccccc2)c2ccc(OC)cc2)cc1 |
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Synonyms
| dmt-nac-dc |
| n-acetyl-5'-dmt deoxycytidine |
