CAS 557-59-5|Lignoceric acid
| Common Name | Lignoceric acid | ||
|---|---|---|---|
| CAS Number | 557-59-5 | Molecular Weight | 368.637 |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 405.9±8.0 °C at 760 mmHg |
| Molecular Formula | C24H48O2 | Melting Point | 80-82 °C |
| MSDS | ChineseUSA | Flash Point | 182.2±13.3 °C |
Names
| Name | lignoceric acid |
|---|---|
| Synonym | More Synonyms |
Lignoceric acid BiologicalActivity
| Description | Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2]. |
|---|---|
| Related Catalog | Research Areas >>Neurological Disease |
| Target | Human Endogenous Metabolite |
| In Vitro | Heat flux induced by lignoceric acid in HepG2 peroxisomes was exothermic, indicating normal peroxisomal metabolism[1]. |
| References | [1]. Anna Petroni, et al. Thermogenic flux induced by lignoceric acid in peroxisomes isolated from HepG2 cells and from X-adrenoleukodystrophy and control fibroblasts. J Cell Physiol. 2019 Aug;234(10):18344-18348. [2]. J M Bourre, et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesis and microsomal malonyl-CoA chain-elongating system in relation to myelination. Comparison between normal mouse and dysmyelinating mutants (quaking and jimpy). Eur J Biochem. 1977 Jan 3;72(1):41-7. |
Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 405.9±8.0 °C at 760 mmHg |
| Melting Point | 80-82 °C |
| Molecular Formula | C24H48O2 |
| Molecular Weight | 368.637 |
| Flash Point | 182.2±13.3 °C |
| Exact Mass | 368.365417 |
| PSA | 37.30000 |
| LogP | 11.40 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.460 |
| InChIKey | QZZGJDVWLFXDLK-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCCCCCCCCCCCCC(=O)O |
| Storage condition | 2-8°C |
Safety Information
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | - |
Articles45
More Articles| HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 37(Database issue) , D603-10, (2009) The Human Metabolome Database (HMDB, http://www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, ... | |
| The human serum metabolome. PLoS ONE 6(2) , e16957, (2011) Continuing improvements in analytical technology along with an increased interest in performing comprehensive, quantitative metabolic profiling, is leading to increased interest pressures within the m... | |
| Development and application of a comparative fatty acid analysis method to investigate voriconazole-induced hepatotoxicity. Clin. Chim. Acta 438 , 126-34, (2014) As fatty acids play an important role in biological regulation, the profiling of fatty acid expression has been used to discover various disease markers and to understand disease mechanisms. This stud... |
Synonyms
| Lignoceric acid |
| Tetracosanoic acid |
| EINECS 209-180-7 |
| MFCD00002810 |
| n-tetracosanoic acid |
