Introduction：Basic information about CAS 3055-94-5|Triethylene glycol monododecyl ether, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Triethylene glycol monododecyl ether |
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| CAS Number | 3055-94-5 | Molecular Weight | 318.492 |
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| Density | 0.9±0.1 g/cm3 | Boiling Point | 412.0±25.0 °C at 760 mmHg |
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| Molecular Formula | C18H38O4 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 202.9±23.2 °C |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | 2-[2-(2-dodecoxyethoxy)ethoxy]ethanol |
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| Synonym | More Synonyms |
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Triethylene glycol monododecyl ether BiologicalActivity
| Description | Triethylene glycol monododecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. |
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Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
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| Boiling Point | 412.0±25.0 °C at 760 mmHg |
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| Molecular Formula | C18H38O4 |
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| Molecular Weight | 318.492 |
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| Flash Point | 202.9±23.2 °C |
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| Exact Mass | 318.277008 |
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| PSA | 47.92000 |
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| LogP | 4.33 |
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| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
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| Index of Refraction | 1.451 |
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| InChIKey | FKMHSNTVILORFA-UHFFFAOYSA-N |
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| SMILES | CCCCCCCCCCCCOCCOCCOCCO |
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| Storage condition | 2-8°C |
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| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- KK7870000
- CHEMICAL NAME :
- Ethanol, 2-(2-(2-(dodecyloxy)ethoxy)ethoxy)-
- CAS REGISTRY NUMBER :
- 3055-94-5
- BEILSTEIN REFERENCE NO. :
- 1779029
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C18-H38-O4
- MOLECULAR WEIGHT :
- 318.56
- WISWESSER LINE NOTATION :
- Q2O2O2O12
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - guinea pig Kidney
- DOSE/DURATION :
- 10 umol/L
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,431,1976
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H319 |
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| Precautionary Statements | P305 + P351 + P338 |
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| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
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| Hazard Codes | Xi: Irritant; |
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| Risk Phrases | R36 |
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| Safety Phrases | S26-S36 |
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| RIDADR | NONH for all modes of transport |
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| RTECS | KK7870000 |
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| HS Code | 2909499000 |
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Customs
| HS Code | 2909499000 |
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| Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
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Synonyms
| Lauryltriglycol ether |
| Triethylene glycol monododecyl ether |
| triiethylene glycol mondodecyl ether |
| PEG-3 Lauryl ether |
| Ethanol, 2-[2-[2-(dodecyloxy)ethoxy]ethoxy]- |
| C12E3 Dodecyl triethylene glycol ether Dodecyltriglycol Polyoxyethylene (3) lauryl ether |
| Dodecyltriglycol |
| 2-{2-[2-(Dodecyloxy)ethoxy]ethoxy}ethanol |
| TRIETHYLENE GLYCOL MONO-N-DODECYL ETHER |
| triethyleneglycol monododecyl ether |
| Dodecyl triethylene glycol ether |
| Lauryl triethoxylate |
| MFCD00042659 |
| Detergent Screening |
| EINECS 221-280-2 |
| Triethylene glycol dodecyl ether |
| Triethyleneglycol monododecyl ether 1 mM |
| Lauryl alcohol triglycol ether |
