Introduction：Basic information about CAS 205687-01-0|Capsiate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Capsiate |
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| CAS Number | 205687-01-0 | Molecular Weight | 306.39700 |
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| Density | / | Boiling Point | 421.3±40.0 °C(Predicted) |
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| Molecular Formula | C18H26O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | (4-hydroxy-3-methoxyphenyl)methyl (E)-8-methylnon-6-enoate |
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| Synonym | More Synonyms |
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Capsiate BiologicalActivity
| Description | Capsiate, as a capsaicin analogue extracted from a non-pungent cultivar of CH-19 sweet red pepper, is an orally active agonist of TRPV1[1]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>TRP ChannelResearch Areas >>Inflammation/Immunology |
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| Target | TRPV1 |
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| In Vitro | Capsiate evokes current responses in HEK293 cells expressing TRPV1[1]. |
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| In Vivo | Capsiate does not exhibit irritancy-related effects on the oral cavity or eye[1]. Capsiate (0.03~0.54 mM; s.c.) induces nociceptive responses in mice[1]. Animal Model: Male ddY-strain mice (20–24 g) [1] Dosage: 0.5 or 5 mM Administration: P.o. Result: Did not cause pungency-related behaviors. |
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| References | [1]. Iida T, et al. TRPV1 activation and induction of nociceptive response by a non-pungent capsaicin-like compound, capsiate. Neuropharmacology. 2003;44(7):958-967. |
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Chemical & Physical Properties
| Boiling Point | 421.3±40.0 °C(Predicted) |
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| Molecular Formula | C18H26O4 |
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| Molecular Weight | 306.39700 |
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| Exact Mass | 306.18300 |
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| PSA | 55.76000 |
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| LogP | 4.21660 |
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| InChIKey | ZICNYIDDNJYKCP-SOFGYWHQSA-N |
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| SMILES | COc1cc(COC(=O)CCCCC=CC(C)C)ccc1O |
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Synonyms
| Capsiate Natura |
| UNII-PX8I7HG5I3 |
| capsiate |
