CAS 35661-40-6|FMOC-L-Phenylalanine

Introduction：Basic information about CAS 35661-40-6|FMOC-L-Phenylalanine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. FMOC-L-Phenylalanine BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Articles4
7. Synonyms

Common Name	FMOC-L-Phenylalanine
CAS Number	35661-40-6	Molecular Weight	387.428
Density	1.3±0.1 g/cm3	Boiling Point	620.1±50.0 °C at 760 mmHg
Molecular Formula	C₂₄H₂₁NO₄	Melting Point	180-187 °C(lit.)
MSDS	ChineseUSA	Flash Point	328.8±30.1 °C

Names

Name	FMOC-L-Phenylalanine
Synonym	More Synonyms

FMOC-L-Phenylalanine BiologicalActivity

Description	Fmoc-Phe-OH is a phenylalanine derivative[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
In Vitro	Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References	[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-816.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	620.1±50.0 °C at 760 mmHg
Melting Point	180-187 °C(lit.)
Molecular Formula	C₂₄H₂₁NO₄
Molecular Weight	387.428
Flash Point	328.8±30.1 °C
Exact Mass	387.147064
PSA	75.63000
LogP	5.41
Vapour Pressure	0.0±1.9 mmHg at 25°C
Index of Refraction	1.633
InChIKey	SJVFAHZPLIXNDH-QFIPXVFZSA-N
SMILES	O=C(NC(Cc1ccccc1)C(=O)O)OCC1c2ccccc2-c2ccccc21
Storage condition	2~8°C

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2924299090

Customs

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles4

Aspartate-modified doxorubicin on its N-terminal increases drug accumulation in LAT1-overexpressing tumors.

Cancer Sci. 106 , 747-56, (2015)

L-type amino acid transporter 1 (LAT1), overexpressed on the membrane of various tumor cells, is a potential target for tumor-targeting therapy. This study aimed to develop a LAT1-mediated chemotherap...

In Vitro and In Vivo Efficacy of Self-Assembling RGD Peptide Amphiphiles for Targeted Delivery of Paclitaxel.

Pharm. Res. 32 , 3087-101, (2015)

The objective of this work was to compare the efficacy of self-assembling cyclic and linear RGD peptide amphiphiles as carriers for delivering paclitaxel to αvβ3 integrin overexpressing tumors.Linear ...

Correlations of amyloid-β concentrations between CSF and plasma in acute Alzheimer mouse model.

Sci. Rep. 4 , 6777, (2014)

Amyloid-β (Aβ) is one of the few neuropathological biomarkers associated with transporters of the blood-brain barrier (BBB). Despite the well-characterized clinical indication of decreasing Aβ levels ...

Synonyms

Fmoc-L-Phc-OH

N-FMOC-PHE-OH

EINECS 252-661-1

L-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

N-Fmoc-(S)-phenylalanine

FMOC-L-PHE-OH

FMOC-L-PHE

N-Fmoc-L-Phe-OH

MFCD00037128

9-fluorenylmethyloxycarbonyl-Phe-OH

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-phenylpropanoic acid

N-FMOC-L-PHE

N-Fmoc-L-phenylalanine

FMOC-PHENYLALANINE

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine

Fmoc-Phe-OH

N-((9H-Fluoren-9-ylmethoxy)carbonyl)-3-phenyl-L-alanine

N-9-Fmoc-L-phenylglycine

FMOC-PHE

N-Fmoc-Phe-OH ( N-Fmoc-L-phenylalanine)

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