Introduction：Basic information about CAS 55612-21-0|2'-Deoxy-2'-fluoro-5-iodouridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-Deoxy-2'-fluoro-5-iodouridine |
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| CAS Number | 55612-21-0 | Molecular Weight | 372.09 |
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| Density | 2.2±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C9H10FIN2O5 | Melting Point | 216-218 °C |
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| MSDS | / | Flash Point | / |
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Names
| Name | 1-[(3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione |
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| Synonym | More Synonyms |
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2'-Deoxy-2'-fluoro-5-iodouridine BiologicalActivity
| Description | 2'-Deoxy-2'-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 2.2±0.1 g/cm3 |
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| Melting Point | 216-218 °C |
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| Molecular Formula | C9H10FIN2O5 |
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| Molecular Weight | 372.09 |
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| Exact Mass | 371.961823 |
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| PSA | 104.81000 |
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| LogP | -0.32 |
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| Index of Refraction | 1.685 |
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| InChIKey | IPVFGAYTKQKGBM-UAKXSSHOSA-N |
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| SMILES | O=c1[nH]c(=O)n(C2OC(CO)C(O)C2F)cc1I |
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| Storage condition | 2-8℃ |
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Synonyms
| 5-Iodo-1-(2-fluoro-2-deoxy-β-D-ribofuranosyl)uracil |
| Uridine, 2'-deoxy-2'-fluoro-5-iodo- |
| Uridine,2'-deoxy-2'-fluoro-5-iodo |
| 2'-Deoxy-2'-fluoro-5-iodouridine |
| 5-Ifdu |
| 2`-epi-Fialuridine |
