CAS 51779-95-4|1,2-Dierucoyl-sn-glycero-3-PC

Introduction：Basic information about CAS 51779-95-4|1,2-Dierucoyl-sn-glycero-3-PC, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 1,2-Dierucoyl-sn-glycero-3-PC BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles6
6. Synonyms

Common Name	1,2-Dierucoyl-sn-glycero-3-PC
CAS Number	51779-95-4	Molecular Weight	898.33
Density	/	Boiling Point	480 °C
Molecular Formula	C₅₂H₁₀₀NO₈P	Melting Point	/
MSDS	ChineseUSA	Flash Point	/

Names

Name	1,2-Dierucoyl-sn-glycero-3-phosphocholine
Synonym	More Synonyms

1,2-Dierucoyl-sn-glycero-3-PC BiologicalActivity

Description	1,2-Dierucoyl-sn-glycero-3-phosphocholine (DEPC) is the composition of liposome membrane. 1,2-Dierucoyl-sn-glycero-3-phosphocholine is used for the preparation of liposomes and studying the properties of lipid bilayers. The GO (glucose oxidase) in the 1,2-Dierucoyl-sn-glycero-3-phosphocholine liposome shows the high activity[1][2].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Masahiro INOUE, et al. Oxidation of Glucose in Gas-Liquid Flow Catalyzed by Glucose Oxidase-Containing Liposomes with Different Acyl Chain Properties. Journal of chemical engineering of japan. Published online, 2013. [2]. Weber ME, et al. Dynamic assessment of bilayer thickness by varying phospholipid and hydraphile synthetic channel chain lengths. J Am Chem Soc. 2005 Jan 19;127(2):636-42.

Description

1,2-Dierucoyl-sn-glycero-3-phosphocholine (DEPC) is the composition of liposome membrane. 1,2-Dierucoyl-sn-glycero-3-phosphocholine is used for the preparation of liposomes and studying the properties of lipid bilayers. The GO (glucose oxidase) in the 1,2-Dierucoyl-sn-glycero-3-phosphocholine liposome shows the high activity[1][2].

Related Catalog

Research Areas >>OthersSignaling Pathways >>Others >>Others

References

[1]. Masahiro INOUE, et al. Oxidation of Glucose in Gas-Liquid Flow Catalyzed by Glucose Oxidase-Containing Liposomes with Different Acyl Chain Properties. Journal of chemical engineering of japan. Published online, 2013.

[2]. Weber ME, et al. Dynamic assessment of bilayer thickness by varying phospholipid and hydraphile synthetic channel chain lengths. J Am Chem Soc. 2005 Jan 19;127(2):636-42.

Chemical & Physical Properties

Boiling Point	480 °C
Molecular Formula	C₅₂H₁₀₀NO₈P
Molecular Weight	898.33
Exact Mass	897.71900
PSA	121.00000
LogP	15.91520
InChIKey	SDEURMLKLAEUAY-JFSPZUDSSA-N
SMILES	CCCCCCCCC=CCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCC=CCCCCCCCC

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

Articles6

Bilayer Effects of Antimalarial Compounds.

PLoS ONE 10 , e0142401, (2015)

Because of the perpetual development of resistance to current therapies for malaria, the Medicines for Malaria Venture developed the Malaria Box to facilitate the drug development process. We tested t...

Whole cell screen for inhibitors of pH homeostasis in Mycobacterium tuberculosis.

PLoS ONE 8 , e68942, (2013)

Bacterial pathogens like Mycobacterium tuberculosis (Mtb) encounter acidic microenvironments in the host and must maintain their acid-base homeostasis to survive. A genetic screen identified two Mtb s...

Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery.

J. Gen. Physiol. 138(2) , 249-70, (2011)

The thiazolidinediones (TZDs) are used in the treatment of diabetes mellitus type 2. Their canonical effects are mediated by activation of the peroxisome proliferator-activated receptor γ (PPARγ) tran...

Synonyms

1,2-di-(13Z-docosenoyl)-sn-glycero-3-phosphocholine

1,2-dierucoyl-sn-glycero-3-phosphocholine

1,2-DI13-CIS-DOCOSENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

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