CAS 851956-02-0|RuBi-4AP

Introduction:Basic information about CAS 851956-02-0|RuBi-4AP, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameRuBi-4AP
CAS Number851956-02-0Molecular Weight672.57
Density/Boiling Point/
Molecular FormulaC30H28Cl2N8RuMelting Point/
MSDS/Flash Point/

Names

NameL-Tryptophan
SynonymMore Synonyms

RuBi-4AP BiologicalActivity

DescriptionRuBi-4AP, a derivative of 4-aminopyridine (4AP; HY-B0604), is a caged Kv channel blocker. RuBi-4AP contains a photolabile protecting group, allowing its effect to be controlled precisely in both space and time with light. RuBi-4AP can be used for the research of neuronal excitability, synaptic transmission, and signal propagation[1][2].
Related CatalogResearch Areas >>Neurological DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>Potassium Channel
References

[1]. Zayat L, et al. A new strategy for neurochemical photodelivery: metal-ligand heterolytic cleavage. J Am Chem Soc. 2003 Jan 29;125(4):882-3.  

[2]. Rowan MJ, et al. Distinct Kv channel subtypes contribute to differences in spike signaling properties in the axon initial segment and presynaptic boutons of cerebellar interneurons. J Neurosci. 2014 May 7;34(19):6611-23.  

Chemical & Physical Properties

Molecular FormulaC30H28Cl2N8Ru
Molecular Weight672.57
Exact Mass204.09000
PSA79.11000
LogP1.82260
InChIKeyMVEGPXUCOGNVKR-UHFFFAOYSA-L
SMILESNc1ccncc1.Nc1ccncc1.[Cl-].[Cl-].[Ru+2].c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1

Synonyms

(S)-(-)-2-Amino-3-(3-indolyl)propionic Acid
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CAS 1283051-39-7|Methyl 2-oxo-3-[2-(trifluoromethyl)phenyl]propanoate
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