Introduction：Basic information about CAS 197922-42-2|Teduglutide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Teduglutide |
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| CAS Number | 197922-42-2 | Molecular Weight | 3752.08000 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C164H252N44O55S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Teduglutide |
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| Synonym | More Synonyms |
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Teduglutide BiologicalActivity
| Description | Teduglutide is a dipeptidyl peptidase IV resistant glucagon-like peptide 2 (GLP-2) analogue. Teduglutide is associated with trophic effects on gut mucosa. Teduglutide can be used for the research of short bowel syndrome (SBS) and Crohn's disease (CD)[1][2]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Jeppesen PB, et al. Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients. Gut. 2005 Sep;54(9):1224-31. [2]. Buchman AL, et al; Teduglutide Study Group. Teduglutide, a novel mucosally active analog of glucagon-like peptide-2 (GLP-2) for the treatment of moderate to severe Crohn's disease. Inflamm Bowel Dis. 2010 Jun;16(6):962-73. |
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Chemical & Physical Properties
| Molecular Formula | C164H252N44O55S |
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| Molecular Weight | 3752.08000 |
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| Exact Mass | 3749.80000 |
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| PSA | 1649.52000 |
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| LogP | 1.01630 |
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| InChIKey | CILIXQOJUNDIDU-ASQIGDHWSA-N |
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| SMILES | CCC(C)C(NC(=O)C(Cc1ccccc1)NC(=O)C(CC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CC(N)=O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(NC(=O)C(CC(N)=O)NC(=O)C(CCSC)NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)CNC(=O)C(N)Cc1cnc[nH]1)C(C)O)C(C)CC)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(=O)NC(CCC(N)=O)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(C(=O)NC(C(=O)NC(CC(=O)O)C(=O)O)C(C)O)C(C)CC)C(C)O)C(C)CC |
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| Storage condition | -20℃ |
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Synonyms
| Revestive |
| ALX 0600 |
| H-His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-OH |
| teduglutide |
| Gattex |
| Glucagon-like peptide II [2-glycine] (human) |
