Introduction:Basic information about CAS 21618-67-7|5-(Trifluoromethyl)uridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-(Trifluoromethyl)uridine |
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| CAS Number | 21618-67-7 | Molecular Weight | 312.20 |
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| Density | 1.765g/cm3 | Boiling Point | / |
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| Molecular Formula | C10H11F3N2O6 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 5-(trifluoromethyl)-uridine |
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| Synonym | More Synonyms |
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5-(Trifluoromethyl)uridine BiologicalActivity
| Description | 5-(Trifluoromethyl)uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.765g/cm3 |
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| Molecular Formula | C10H11F3N2O6 |
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| Molecular Weight | 312.20 |
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| Exact Mass | 312.05700 |
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| PSA | 124.78000 |
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| Index of Refraction | 1.563 |
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| InChIKey | UEJHQHNFRZXWRD-UAKXSSHOSA-N |
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| SMILES | O=c1[nH]c(=O)n(C2OC(CO)C(O)C2O)cc1C(F)(F)F |
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Synonyms
| 5-trifluorouridine |
| 500Mg,1g |
| 5-trifluorothymidine |
| 5-(trifluoromethyl)uridine |