CAS 55297-95-5|Tiamulin
| Common Name | Tiamulin | ||
|---|---|---|---|
| CAS Number | 55297-95-5 | Molecular Weight | 493.742 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 563.0±50.0 °C at 760 mmHg |
| Molecular Formula | C28H47NO4S | Melting Point | 147-148ºC |
| MSDS | ChineseUSA | Flash Point | 294.3±30.1 °C |
Names
| Name | tiamulin |
|---|---|
| Synonym | More Synonyms |
Tiamulin BiologicalActivity
| Description | Tiamulin (Thiamutilin) is a diterpenic veterinary drug widely used in swine for the control of infectious diseases, including swine dysentery and enzootic pneumonia[1][2][3]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
| References | [1]. Noa M, et al. Tiamulin-nitrovin interaction in pigs: a case report and experimental reproduction. Vet Hum Toxicol. 2000 Oct;42(5):286-8. [2]. Dreyfuss J, et al. Metabolism of tritium- and carbon-14-labeled tiamulin in dogs, rats, and pigs. J Antibiot (Tokyo). 1979 May;32(5):496-503. [3]. Islam KM, et al. The activity and compatibility of the antibiotic tiamulin with other drugs in poultry medicine--A review. Poult Sci. 2009 Nov;88(11):2353-9. |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 563.0±50.0 °C at 760 mmHg |
| Melting Point | 147-148ºC |
| Molecular Formula | C28H47NO4S |
| Molecular Weight | 493.742 |
| Flash Point | 294.3±30.1 °C |
| Exact Mass | 493.322571 |
| PSA | 92.14000 |
| LogP | 5.93 |
| Vapour Pressure | 0.0±3.5 mmHg at 25°C |
| Index of Refraction | 1.541 |
| InChIKey | UURAUHCOJAIIRQ-UHFFFAOYSA-N |
| SMILES | C=CC1(C)CC(OC(=O)CSCCN(CC)CC)C2(C)C(C)CCC3(CCC(=O)C32)C(C)C1O |
| Storage condition | 2-8°C |
Safety Information
| Hazard Statements | H413 |
|---|---|
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | Xn |
| RIDADR | NONH for all modes of transport |
| RTECS | AG9552000 |
Articles25
More Articles| [Effect of different compatibility of tetramethylpyrazine on its pharmacokinetics in vivo]. Zhongguo Zhong Yao Za Zhi 37(9) , 1311-4, (2012) To study the pharmacokinetics of single administration and different compatibility of tetramethylpyrazine (TMP) in rats.Thirty two Sprague-Dawley rats were randomly divided into 4 groups: the TMP (30 ... | |
| Design, synthesis, and antibacterial activity of novel pleuromutilin derivatives bearing an amino thiazolyl ring. Arch. Pharm. (Weinheim) 345(8) , 638-46, (2012) A series of novel pleuromutilin derivatives containing the amino thiazolyl ring were designed, synthesized, and evaluated for their antibacterial activities in vitro against Gram-positive clinical bac... | |
| Simultaneous determination of three classes of antibiotics in the suspended solids of swine wastewater by ultrasonic extraction, solid-phase extraction and liquid chromatography-mass spectrometry. J. Environ. Sci. (China) 23(10) , 1729-37, (2011) This work describes a systematic approach to the development of a method for simultaneous determination of three classes of veterinary antibiotics in the suspended solids (SS) of swine wastewater, inc... |
Synonyms
| Tiamulin |
| EINECS 259-580-0 |
| MFCD01672098 |
| thiamutilin |
| TiaMulin fuMerate API |
| 14-Desoxy-14-[(2-diethylaminoethyl)mercaptoacetoxy]mutilin |
| (1S,2R,3S,4S,6R,7R,8R,14R)-3-Hydroxy-2,4,7,14-tetramethyl-9-oxo-4-vinyltricyclo[5.4.3.0]tetradec-6-yl {[2-(diethylamino)ethyl]sulfanyl}acetate |
| tiavetp |
| Tiamutin |
| Acetic acid, 2-[[2-(diethylamino)ethyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester |
| TIAMILIN |
