CAS 59619-81-7|(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-2-[2-(phenoxymethyl)-1,3-dioxolan-2-yl]ethe

Introduction：Basic information about CAS 59619-81-7|(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-2-[2-(phenoxymethyl)-1,3-dioxolan-2-yl]ethe, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Synonyms

Common Name	(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-2-[2-(phenoxymethyl)-1,3-dioxolan-2-yl]ethenyl]cyclopentyl]hept-5-enoic acid
CAS Number	59619-81-7	Molecular Weight	432.507
Density	1.3±0.1 g/cm3	Boiling Point	598.1±50.0 °C at 760 mmHg
Molecular Formula	C₂₄H₃₂O₇	Melting Point	/
MSDS	/	Flash Point	200.2±23.6 °C

Names

Name	(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-2-[2-(phenoxymethyl)-1,3-dioxolan-2-yl]ethenyl]cyclopentyl]hept-5-enoic acid
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	598.1±50.0 °C at 760 mmHg
Molecular Formula	C₂₄H₃₂O₇
Molecular Weight	432.507
Flash Point	200.2±23.6 °C
Exact Mass	432.214813
PSA	105.45000
LogP	1.66
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.633
InChIKey	BPALXSWPHQNCAA-UHFFFAOYSA-N
SMILES	O=C(O)CCCC=CCC1C(O)CC(O)C1C=CC1(COc2ccccc2)OCCO1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MJ9671000

CHEMICAL NAME :: 5-Heptenoic acid, 7-(3,5-dihydroxy-2-(2-(2-(phenoxymethyl)-1,3-dioxolan -2-yl)ethenyl) cyclopentyl)-, (1R-(1-alpha(Z),2-beta(E),3-alpha,5-alpha))-

CAS REGISTRY NUMBER :: 59619-81-7

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C24-H32-O7

MOLECULAR WEIGHT :: 432.56

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 600 ug/kg

SEX/DURATION :: female 4-7 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - abortion

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 21,443,1978

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 25 ug/kg

SEX/DURATION :: female 29 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - parturition Reproductive - Effects on Newborn - stillbirth Reproductive - Effects on Newborn - physical

REFERENCE :: ANIPA8 Animal Production. (Scotish Academic Press Ltd., 33 Montgomery Street, Edinburgh EH7 5JX, UK) V.1- 1959- Volume(issue)/page/year: 49,129,1989

Synonyms

(5Z)-7-[(1R,2R,3R)-3,5-Dihydroxy-2-{(E)-2-[2-(phenoxymethyl)-1,3-dioxolan-2-yl]vinyl}cyclopentyl]-5-heptenoic acid

15-Deoxy-15,15-ethylenedioxy-16-phenoxy-17,18,19,20-tetranorprostaglandinF2a

Etiprostone [INN-French]

(5Z,13E)-(8R,9S,11R,12R)-9,11-Dihydroxy-15,15-ethylenedioxy-16-phenoxy-17,18,19,20-tetranorprostadienoic Acid

Etiprostonum [INN-Latin]

Etiprostone

Etiprostonum

Etiproston

5-Heptenoic acid, 7-[(1R,2R,3R)-3,5-dihydroxy-2-[(E)-2-[2-(phenoxymethyl)-1,3-dioxolan-2-yl]ethenyl]cyclopentyl]-, (5Z)-

(5Z)-7-[(1R,2R,3R)-3,5-Dihydroxy-2-{(E)-2-[2-(phenoxymethyl)-1,3-dioxolan-2-yl]vinyl}cyclopentyl]hept-5-enoic acid

(5Z,13E)-(8R,9S,11R,12R)-9,11-dihydroxy-15,15-ethylenedioxy-16-phenoxy-17,18,19,20-tetranor-prostadienoic acid

Etiproston (INN)

(5Z)-7-[(1R,2R,3R)-3,5-dihydroxy-2-{(E)-2-[2-(phenoxymethyl)-1,3-dioxolan-2-yl]ethenyl}cyclopentyl]hept-5-enoic acid

[1R-(1a(Z),2b(E),3a,5a)]-7-[3,5-Dihydroxy-2-[2-[2-(phenoxymethyl)-1,3-dioxolan-2-yl]ethenyl]cyclopentyl]-5-heptenoic Acid

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