CAS 12650-69-0|Mupirocin
| Common Name | Mupirocin | ||
|---|---|---|---|
| CAS Number | 12650-69-0 | Molecular Weight | 500.622 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 672.3±55.0 °C at 760 mmHg |
| Molecular Formula | C26H44O9 | Melting Point | 77-780C |
| MSDS | ChineseUSA | Flash Point | 216.5±25.0 °C |
Names
| Name | mupirocin |
|---|---|
| Synonym | More Synonyms |
Mupirocin BiologicalActivity
| Description | Mupirocin(BRL-4910A) is an antibiotic of the monoxycarbolic acid class; effective against Gram-positive bacteria, including MRSA. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection |
| References | [1]. Hughes J, et al. Inhibition of isoleucyl-transfer ribonucleic acid synthetase in Escherichia coli by pseudomonic acid. Biochem J. 1978 Oct 15;176(1):305-18. [2]. Cookson BD. The emergence of mupirocin resistance: a challenge to infection control and antibiotic prescribing practice. J Antimicrob Chemother. 1998 Jan;41(1):11-8. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 672.3±55.0 °C at 760 mmHg |
| Melting Point | 77-780C |
| Molecular Formula | C26H44O9 |
| Molecular Weight | 500.622 |
| Flash Point | 216.5±25.0 °C |
| Exact Mass | 500.298523 |
| PSA | 146.05000 |
| LogP | 3.44 |
| Vapour Pressure | 0.0±4.7 mmHg at 25°C |
| Index of Refraction | 1.524 |
| InChIKey | MINDHVHHQZYEEK-HBBNESRFSA-N |
| SMILES | CC(=CC(=O)OCCCCCCCCC(=O)O)CC1OCC(CC2OC2C(C)C(C)O)C(O)C1O |
| Storage condition | -20°C Freezer, Under Inert Atmosphere |
| Water Solubility | H2O: 12 mg/mL, soluble |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Safety Phrases | S2 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | RA6907000 |
| HS Code | 2941909000 |
Customs
| HS Code | 2941909000 |
|---|
Articles98
More Articles| Purification and characterization of the Staphylococcus aureus bacillithiol transferase BstA. Biochim. Biophys. Acta 1840(9) , 2851-61, (2014) Gram-positive bacteria in the phylum Firmicutes synthesize the low molecular weight thiol bacillithiol rather than glutathione or mycothiol. The bacillithiol transferase YfiT from Bacillus subtilis wa... | |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). J. Sci. Ind. Res. 65(10) , 808, (2006) Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI typ... | |
| Simultaneous monitoring of Staphylococcus aureus growth in a multi-parametric microfluidic platform using microscopy and impedance spectroscopy. Bioelectrochemistry 105 , 56-64, (2015) We describe the design, construction, and characterization of a scalable microfluidic platform that allows continuous monitoring of biofilm proliferation under shear stress conditions. Compared to oth... |
Synonyms
| Pseudomonic acid |
| 9-({(2E)-4-[(2S,3R,4R,5S)-3,4-Dihydroxy-5-({(2S,3S)-3-[(2S,3S)-3-hydroxy-2-butanyl]-2-oxiranyl}methyl)tetrahydro-2H-pyran-2-yl]-3-methyl-2-butenoyl}oxy)nonanoic acid |
| 9-({(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-({(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiran-2-yl}methyl)tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoyl}oxy)nonanoic acid (non-preferred name) |
| Bactoderm |
| MFCD03792664 |
| Pseudomonic acid A |
| Mupirocin |
| EINECS 231-791-2 |
| Turixin |
| BACTROBAN |
| Mupirocin [USAN:BAN:INN] |
| Mupirocina |
| trans-Pseudomonic Acid |
| Bactroban Nasal |
| Plasimine |
| 9-({(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-({(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiran-2-yl}methyl)tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoyl}oxy)nonanoic acid |
| 9-({(2E)-4-[(2S,3R,4R,5S)-3,4-Dihydroxy-5-({(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}methyl)tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoyl}oxy)nonanoic acid (non-preferred name) |
| Mupirocine |
| Mupirocinum |
| [2S-[2a(E),3b,4b,5a[2R*,3R*(1R*,2R*)]]]-9-[[3-Methyl-1-oxo-4-[tetrahydro-3,4-dihydroxy-5-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-2H-pyran-2-yl]-2-butenyl]oxy]nonanoic Acid |
| Centany |
| 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl]oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid |
