CAS 21411-53-0|Virginiamycin M1
Introduction：Basic information about CAS 21411-53-0|Virginiamycin M1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Virginiamycin M1 | ||
|---|---|---|---|
| CAS Number | 21411-53-0 | Molecular Weight | 525.59300 |
| Density | 1.26 g/cm3 | Boiling Point | 825.2ºC at 760 mmHg |
| Molecular Formula | C28H35N3O7 | Melting Point | 165-170 °C |
| MSDS | ChineseUSA | Flash Point | 452.9ºC |
Names
| Name | pristinamycin IIA |
|---|---|
| Synonym | More Synonyms |
Virginiamycin M1 BiologicalActivity
| Description | Pristinamycin IIA (RP 12536) is a macrocyclic lactone peptolide antibiotic, derived from Streptomyces pristinaespiralis, which is a member of the streptogramin A group of antibiotics[1]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
| Target | Bacterial[1] |
| References | [1]. Sezonov G, et al. Complete conversion of antibiotic precursor to pristinamycin IIA by overexpression of Streptomyces pristinaespiralis biosynthetic genes. Nat Biotechnol. 1997 Apr;15(4):349-53. |
Chemical & Physical Properties
| Density | 1.26 g/cm3 |
|---|---|
| Boiling Point | 825.2ºC at 760 mmHg |
| Melting Point | 165-170 °C |
| Molecular Formula | C28H35N3O7 |
| Molecular Weight | 525.59300 |
| Flash Point | 452.9ºC |
| Exact Mass | 525.24800 |
| PSA | 139.04000 |
| LogP | 2.92610 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.586 |
| InChIKey | DAIKHDNSXMZDCU-XMERXJNXSA-N |
| SMILES | CC1=CC(O)CC(=O)Cc2nc(co2)C(=O)N2CCC=C2C(=O)OC(C(C)C)C(C)C=CC(=O)NCC=C1 |
| Storage condition | -20°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3.0 |
Articles3
More Articles| Purification and characterization of virginiamycin M1 reductase from Streptomyces virginiae. Antimicrob. Agents Chemother. 42 , 2985-2988, (1998) Virginiamycin M1 (VM1), produced by Streptomyces virginiae, is a polyunsaturated macrocyclic lactone antibiotic belonging to the virginiamycin A group. S. virginiae possesses an activity which stereos... | |
| PapR6, a putative atypical response regulator, functions as a pathway-specific activator of pristinamycin II biosynthesis in Streptomyces pristinaespiralis. J. Bacteriol. 197(3) , 441-50, (2015) There are up to seven regulatory genes in the pristinamycin biosynthetic gene cluster of Streptomyces pristinaespiralis, which infers a complicated regulation mechanism for pristinamycin production. I... | |
| VisG is eβential for biosynthesis of virginiamycin S, a streptogramin type B antibiotic, as a provider of the nonproteinogenic amino acid phenylglycine Fitria Ningsih, Shigeru Kitani, et al. Microbiology 167 , 3213 - 3220, (2011) |
Synonyms
| Vernamycin A |
| Staphylomycin M1 |
| STAPHYLOMYCIN |
| Antibiotic PA-114A1 |
| pristinamycin component IIA |
| VIRGINIAMYCINE |
| MIKAMYCIN A |
| Pristinamycin IIA |
| VIRGINIAMYCIN M1 |
| Streptogramin A |
