Introduction：Basic information about CAS 120138-50-3|Quinupristin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Quinupristin |
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| CAS Number | 120138-50-3 | Molecular Weight | 1022.22000 |
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| Density | 1.38g/cm3 | Boiling Point | / |
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| Molecular Formula | C53H67N9O10S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
Quinupristin BiologicalActivity
| Description | Quinupristin is a streptogramin antibiotic. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits[1] [2]. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>Bacterial |
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| In Vitro | Quinupristin/dalfopristin is a combination of streptogramin antibiotics used to against infections.Quinupristin/dalfopristin targets the 23S rRNA of most Gram-positive bacteria as well as those of certain Gram-negative bacteria[1]. Quinupristin/dalfopristin is reportedly effective against Mycoplasma spp[1]. |
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| References | [1]. Gurk-Turner C. Quinupristin/dalfopristin: the first available macrolide-lincosamide-streptogramin antibiotic. Proc (Bayl Univ Med Cent). 2000 Jan;13(1):83-6. [2]. Tantibhedhyangkul W, et al. Anti-Mycoplasma Activity of Daptomycin and Its Use for Mycoplasma Elimination in Cell Cultures of Rickettsiae. Antibiotics (Basel). 2019 Aug 21;8(3). |
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Chemical & Physical Properties
| Density | 1.38g/cm3 |
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| Molecular Formula | C53H67N9O10S |
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| Molecular Weight | 1022.22000 |
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| Exact Mass | 1021.47000 |
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| PSA | 256.50000 |
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| LogP | 3.12360 |
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| Index of Refraction | 1.662 |
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| InChIKey | WTHRRGMBUAHGNI-KNIYECGFSA-N |
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| SMILES | CCC1NC(=O)C(NC(=O)c2ncccc2O)C(C)OC(=O)C(c2ccccc2)NC(=O)C2CC(=O)C(CSC3CN4CCC3CC4)CN2C(=O)C(Cc2ccc(N(C)C)cc2)N(C)C(=O)C2CCCN2C1=O |
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