Introduction：Basic information about CAS 518-69-4|Corydaline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Corydaline |
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| CAS Number | 518-69-4 | Molecular Weight | 369.454 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 482.3±45.0 °C at 760 mmHg |
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| Molecular Formula | C22H27NO4 | Melting Point | 135° |
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| MSDS | / | Flash Point | 135.7±25.9 °C |
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Names
| Name | corydaline |
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| Synonym | More Synonyms |
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Corydaline BiologicalActivity
| Description | Corydaline is an acetylcholinesterase inhibitor isolated from Corydalis yanhusuo. |
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| Related Catalog | Signaling Pathways >>Neuronal Signaling >>AChENatural Products >>AlkaloidResearch Areas >>Neurological Disease |
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| References | [1]. Xiao HT, et al. Acetylcholinesterase inhibitors from Corydalis yanhusuo. Nat Prod Res. 2011 Sep;25(15):1418-22. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 482.3±45.0 °C at 760 mmHg |
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| Melting Point | 135° |
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| Molecular Formula | C22H27NO4 |
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| Molecular Weight | 369.454 |
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| Flash Point | 135.7±25.9 °C |
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| Exact Mass | 369.194000 |
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| PSA | 40.16000 |
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| LogP | 4.19 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.600 |
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| InChIKey | VRSRXLJTYQVOHC-YEJXKQKISA-N |
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| SMILES | COc1cc2c(cc1OC)C1C(C)c3ccc(OC)c(OC)c3CN1CC2 |
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| Storage condition | -20°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- GN0600000
- CHEMICAL NAME :
- Corydaline
- CAS REGISTRY NUMBER :
- 518-69-4
- BEILSTEIN REFERENCE NO. :
- 0096972
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C22-H27-N-O4
- MOLECULAR WEIGHT :
- 369.50
- WISWESSER LINE NOTATION :
- T D6 B666 KN&TT&J C1 GO1 HO1 PO1 QO1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 136 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 5,163,1946
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Synonyms
| 13aβ-Berbine, 2,3,9,10-tetramethoxy-13α-methyl- |
| (13S,13aR)-2,3,9,10-tetramethoxy-13-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline |
| d-Corydalin |
| (13S,13aR)-2,3,9,10-Tetramethoxy-13-methyl-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinoline |
| (13S-trans )-5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-13-methyl-6H-dibenzo[a,g]quinolizine |
| Corydaline (+) |
| 6H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-, (13S,13aR)- |
| Berbine,2,3,9,10-tetramethoxy-13-methyl |
| 2,3,9,10-Tetramethoxy-13a-methyl-13ab-berbine |
| (13S,13aR)-2,3,9,10-Tetramethoxy-13-methyl-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline |
| Corydalin |
| Corydaline |
