CAS 117961-27-0|Tos-Gly-Pro-Arg-AMC · HCl

Introduction:Basic information about CAS 117961-27-0|Tos-Gly-Pro-Arg-AMC · HCl, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameTos-Gly-Pro-Arg-AMC · HCl
CAS Number117961-27-0Molecular Weight676.18300
Density1.46g/cm3Boiling Point/
Molecular FormulaC30H38ClN7O7SMelting Point/
MSDSUSAFlash Point/

Names

NameN-p-Tosyl-Gly-Pro-Arg 7-amido-4-methylcoumarin hydrochloride
SynonymMore Synonyms

Chemical & Physical Properties

Density1.46g/cm3
Molecular FormulaC30H38ClN7O7S
Molecular Weight676.18300
Exact Mass675.22400
PSA225.17000
LogP4.93230
Index of Refraction1.676

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport
WGK Germany3

Articles2

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Activating a zymogen without proteolytic processing: mutation of Lys15 and Asn194 activates trypsinogen.

Biochemistry 37(46) , 16201-10, (1998)

The zymogen and mature enzyme forms of trypsin-like serine proteases exhibit a wide range of activities. The prototypical trypsinogen-trypsin system is an example of a minimally active zymogen and a m...

[A photometric method of determining the activity of antithrombin III using a peptide coumarylamide substrate].

Lab. Delo (8) , 43-5, (1990)

Toz-Gly-Pro-Arg-4-methylcoumaryl-7-amide is recommended for antithrombin-III (AT-III) photometry as a substrate. This substrate is cleaved by thrombin at 366 nm. AT-III photometry with this substrate ...

Synonyms

n-p-tosyl-gly-pro-arg 7-amido-4-methylcoumarin hydrochloride
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