CAS 67-51-6|3,5-Dimethylpyrazole

Introduction：Basic information about CAS 67-51-6|3,5-Dimethylpyrazole, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles27
7. Synonyms

Common Name	3,5-Dimethylpyrazole
CAS Number	67-51-6	Molecular Weight	96.130
Density	1.0±0.1 g/cm3	Boiling Point	218.0±0.0 °C at 760 mmHg
Molecular Formula	C₅H₈N₂	Melting Point	105-108 °C(lit.)
MSDS	ChineseUSA	Flash Point	90.5±11.7 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	3,5-Dimethylpyrazole
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	218.0±0.0 °C at 760 mmHg
Melting Point	105-108 °C(lit.)
Molecular Formula	C₅H₈N₂
Molecular Weight	96.130
Flash Point	90.5±11.7 °C
Exact Mass	96.068748
PSA	28.68000
LogP	1.24
Vapour Pressure	0.2±0.4 mmHg at 25°C
Index of Refraction	1.520
InChIKey	SDXAWLJRERMRKF-UHFFFAOYSA-N
SMILES	Cc1cc(C)[nH]n1
Water Solubility	methanol: 0.1 g/mL, clear

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UQ6477600

CHEMICAL NAME :: Pyrazole, 3,5-dimethyl-

CAS REGISTRY NUMBER :: 67-51-6

BEILSTEIN REFERENCE NO. :: 0106325

LAST UPDATED :: 199709

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C5-H8-N2

MOLECULAR WEIGHT :: 96.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,23,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1060 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - ataxia

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(10),56,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 570 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay)

REFERENCE :: DPHFAK Dissertationes Pharmaceuticae et Pharmacologicae. (Warsaw, Poland) V.18-24, 1966-72. For publisher information, see PJPPAA. Volume(issue)/page/year: 18,19,1966 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1620 No. of Facilities: 89 (estimated) No. of Industries: 5 No. of Occupations: 7 No. of Employees: 315 (estimated) No. of Female Employees: 109 (estimated)

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R22;R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	UQ6477600
HS Code	2933199090

Customs

HS Code	2933199090
Summary	2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles27

Stimulation of autophagy by antilipolytic drugs may rescue rodents from age-associated hypercholesterolemia.

Rejuvenation Res. 12(2) , 77-84, (2009)

Aging is characterized by several metabolic changes responsible for the decline of certain functions and the appearance of age-related diseases, including hypercholesterolemia, which is the main risk ...

Vibrational spectra of 3,5-dimethylpyrazole and deuterated derivatives.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 56A(8) , 1469-98, (2000)

The infrared (IR) and Raman spectra of 3,5-dimethylpyrazole have been recorded in the vapor, liquid (melt and solution) and solid states. Two deuterated derivatives, C5H7N-ND and C5D7N-NH, were also s...

Effects of antilipolytic agents on peroxisomal beta-oxidation of fatty acids in rat liver.

Biochem. Pharmacol. 32(11) , 1807-9, (1983)

Synonyms

MFCD00005243

EINECS 200-657-5

3,5-Dimethyl-1H-pyrazole

1H-Pyrazole, 3,5-dimethyl-

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