Introduction：Basic information about CAS 142929-49-5|Boc-O1Pen-OH * DCHA, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Boc-O1Pen-OH * DCHA |
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| CAS Number | 142929-49-5 | Molecular Weight | 219.235 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 391.2±22.0 °C at 760 mmHg |
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| Molecular Formula | C9H17NO5 | Melting Point | / |
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| MSDS | / | Flash Point | 190.4±22.3 °C |
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Names
| Name | 2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]acetic acid |
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| Synonym | More Synonyms |
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Boc-O1Pen-OH * DCHA BiologicalActivity
| Description | Boc-NH-PEG1-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs Alkyl/ether |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 391.2±22.0 °C at 760 mmHg |
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| Molecular Formula | C9H17NO5 |
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| Molecular Weight | 219.235 |
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| Flash Point | 190.4±22.3 °C |
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| Exact Mass | 219.110672 |
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| PSA | 84.86000 |
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| LogP | 0.55 |
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| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
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| Index of Refraction | 1.462 |
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| InChIKey | UPBQMAHYLWJGDW-UHFFFAOYSA-N |
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| SMILES | CC(C)(C)OC(=O)NCCOCC(=O)O |
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Safety Information
Customs
| HS Code | 2924199090 |
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| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| Acetic acid, 2-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]- |
| {2-[(tert-Butoxycarbonyl)amino]ethoxy}acetic acid |
| [2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)ethoxy]acetic acid |
| AmbotzBAA5240 |
