Introduction：Basic information about CAS 2673-72-5|D-erythro-Sphingosine hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | D-erythro-Sphingosine hydrochloride |
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| CAS Number | 2673-72-5 | Molecular Weight | 335.95300 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C18H38ClNO2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | D-erythro-Sphingosine hydrochloride |
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| Synonym | More Synonyms |
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D-erythro-Sphingosine hydrochloride BiologicalActivity
| Description | D-erythro-Sphingosine (Erythrosphingosine) hydrochloride is a specific TRPM3 activator. D-erythro-Sphingosine also induces retinoblastoma protein dephosphorylation[1][2]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>TRP ChannelResearch Areas >>Neurological Disease |
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| Target | TRPM3 Retinoblastoma protein |
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| In Vitro | Extracellular application of D-erythro-Sphingosine (20 μM) induces an increase in [Ca2+]i in TRPM3-transfected HEK293 cells within 20 to 30 s after start of application, whereas nontransfected control cells (NT) shows only very small responses[1]. D-erythro-Sphingosine (10 μM) induces currents through TRPM3[1]. Induction of retinoblastoma protein dephosphorylation by D-erythro-Sphingosine (500 nM; 24 h) precede inhibition of growth and a specific arrest in the G0/G1 phase of the cell cycle[2]. |
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Chemical & Physical Properties
| Molecular Formula | C18H38ClNO2 |
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| Molecular Weight | 335.95300 |
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| Exact Mass | 335.25900 |
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| PSA | 66.48000 |
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| LogP | 5.42650 |
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| InChIKey | YDIHJJLAPMAISR-ZNWYJMOFSA-N |
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| SMILES | CCCCCCCCCCCCCC=CC(O)C(N)CO.Cl |
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Synonyms
