Introduction：Basic information about CAS 20869-95-8|Ermanin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ermanin |
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| CAS Number | 20869-95-8 | Molecular Weight | 314.289 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | 552.0±50.0 °C at 760 mmHg |
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| Molecular Formula | C17H14O6 | Melting Point | / |
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| MSDS | / | Flash Point | 206.9±23.6 °C |
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Names
| Name | 5,7-dihydroxy-3-methoxy-2-(4-methoxyphenyl)chromen-4-one |
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| Synonym | More Synonyms |
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Ermanin BiologicalActivity
| Description | Ermanin is a flavonoid isolated from Tanacetum microphyllum. Ermanin potently inhibits iNOS, COX-2 activities, and inhibits platelet aggregation. Ermanin has anti-inflammatory, anti-tuberculous and anti-viral/bacterial properties[1][2]. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>Influenza VirusResearch Areas >>Cardiovascular DiseaseResearch Areas >>InfectionSignaling Pathways >>Immunology/Inflammation >>NO SynthaseResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Immunology/Inflammation >>COXSignaling Pathways >>Anti-infection >>Bacterial |
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| Target | COX-2 iNOS Bacterial |
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| References | [1]. Sandeep Appunni, et al. Targeting PknB, an Eukaryotic-Like serine/threonine Protein Kinase of Mycobacterium Tuberculosis With Phytomolecules. Comput Biol Chem. 2017 Apr;67:200-204. [2]. Jih-Jung Chen, et al. New Sesquiterpenoids and Anti-Platelet Aggregation Constituents From the Rhizomes of Curcuma Zedoaria. Molecules. 2016 Oct 17;21(10):1385. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 552.0±50.0 °C at 760 mmHg |
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| Molecular Formula | C17H14O6 |
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| Molecular Weight | 314.289 |
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| Flash Point | 206.9±23.6 °C |
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| Exact Mass | 314.079041 |
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| PSA | 89.13000 |
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| LogP | 2.40 |
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| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
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| Index of Refraction | 1.671 |
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| InChIKey | RJCJVIFSIXKSAH-UHFFFAOYSA-N |
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| SMILES | COc1ccc(-c2oc3cc(O)cc(O)c3c(=O)c2OC)cc1 |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2914509090 |
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Customs
| HS Code | 2914509090 |
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| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
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Synonyms
| 5,7-Dihydroxy-3,4'-dimethoxyflavone |
| 5,7-Dihydroxy-3-methoxy-2-(4-methoxy-; phenyl)-chromen-4-one |
| 5,7-Dihydroxy-3-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one |
| 3,4'-Dimethoxychrysin |
| Kaempferol 3,4'-di-O-methyl ether |
| Ermanin |
| 3',5,7-trihydroxy-3,4'-dimethoxyflavone |
| 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-methoxy-2-(4-methoxyphenyl)- |
| Kaempferol-3,4'-dimethylether |
| kaempferol 3,4'-dimethyl ether |
| 3,4'-dimethoxykaempferol |
| 5,7-dihydroxy-3-methoxy-2-(4-methoxyphenyl)-4-benzopyrone |
