CAS 35306-33-3|GELSEMINE HYDROCHLORIDE

CHEMICAL IDENTIFICATION

RTECS NUMBER :

LX9150000

CHEMICAL NAME :

Gelsemine, monohydrochloride

CAS REGISTRY NUMBER :

35306-33-3

LAST UPDATED :

199203

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C20-H22-N2-O2.Cl-H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

4 mg/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :

DUSA** "Dispensatory of the United States of America," 24th ed., Osol, A. and G.E. Farrar, Philadelphia, J.B. Lippincott Co., 1947 Volume(issue)/page/year: 24,497,1947

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

500 ug/kg

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - other changes Liver - other changes Kidney, Ureter, Bladder - other changes

REFERENCE :

ZEBLA3 Zeitschrift fuer Biologie. (Munich, Fed. Rep. Ger.) V.1-116, 1865-1971. Discontinued. Volume(issue)/page/year: 99,446,1939