Introduction：Basic information about CAS 354815-90-0|MurA-IN-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | MurA-IN-1 |
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| CAS Number | 354815-90-0 | Molecular Weight | 215.25 |
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| Density | 1.25g/cm3 | Boiling Point | 406.5ºC at 760 mmHg |
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| Molecular Formula | C13H13NO2 | Melting Point | / |
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| MSDS | USA | Flash Point | 199.7ºC |
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| Symbol |
GHS06 | Signal Word | Danger |
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Names
| Name | 3a,4,5,9b-tetrahydro-3h-cyclopenta[c]quinoline-4-carboxylic acid |
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MurA-IN-1 BiologicalActivity
| Description | MurA-IN-1 (compound 1a) is a PTPRR inhibitor, with IC50 values of 0.23 μM, 0.8 μM, 0.75 μM and 0.09 μM for PTP1B, PTPN5, PTPN7 and PTPRR, respectively[1]. (A family of human MAPK-specific protein tyrosine phosphatases) |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| Target | IC50: 0.23 μM (PTP1B), 0.8 μM (PTPN5), 0.75 μM (PTPN7), 0.09 μM (PTPRR)[1]. |
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| References | [1]. Jeyanthy Eswaran, et al. Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases. Biochem J. 2006 May 1;395(3):483-91. |
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Chemical & Physical Properties
| Density | 1.25g/cm3 |
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| Boiling Point | 406.5ºC at 760 mmHg |
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| Molecular Formula | C13H13NO2 |
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| Molecular Weight | 215.25 |
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| Flash Point | 199.7ºC |
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| Exact Mass | 215.09500 |
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| PSA | 49.33000 |
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| LogP | 2.36300 |
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| Index of Refraction | 1.606 |
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| InChIKey | WRJCENKZISEXPF-UHFFFAOYSA-N |
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| SMILES | O=C(O)C1Nc2ccccc2C2C=CCC12 |
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Safety Information
| Symbol |
GHS06 |
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| Signal Word | Danger |
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| Hazard Statements | H301 |
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| Precautionary Statements | P301 + P310 |
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| Hazard Codes | Xi |
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| RIDADR | UN 2811 6.1 / PGIII |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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