Introduction：Basic information about CAS 1455-77-2|1H-1,2,4-Triazole-3,5-diamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 1H-1,2,4-Triazole-3,5-diamine |
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| CAS Number | 1455-77-2 | Molecular Weight | 99.095 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 473.7±28.0 °C at 760 mmHg |
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| Molecular Formula | C2H5N5 | Melting Point | 202-205 °C(lit.) |
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| MSDS | / | Flash Point | 271.6±11.2 °C |
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Names
| Name | guanazole |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 473.7±28.0 °C at 760 mmHg |
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| Melting Point | 202-205 °C(lit.) |
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| Molecular Formula | C2H5N5 |
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| Molecular Weight | 99.095 |
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| Flash Point | 271.6±11.2 °C |
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| Exact Mass | 99.054497 |
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| PSA | 93.61000 |
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| LogP | -1.61 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.810 |
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| InChIKey | PKWIYNIDEDLDCJ-UHFFFAOYSA-N |
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| SMILES | Nc1n[nH]c(N)n1 |
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| Stability | Stability Air sensitive. Reacts with acids and oxidizing agents. |
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| Water Solubility | H2O: clear to hazy |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- XZ4535000
- CHEMICAL NAME :
- s-Triazole, 3,5-diamino-
- CAS REGISTRY NUMBER :
- 1455-77-2
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C2-H5-N5
- MOLECULAR WEIGHT :
- 99.12
- WISWESSER LINE NOTATION :
- T5MN DNJ CZ EZ
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 8620 mg/kg/5D
- TOXIC EFFECTS :
- Blood - leukopenia Blood - thrombocytopenia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- >316 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2500 mg/kg/7W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Endocrine - tumors Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 9750 mg/kg/26W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - lymphoma, including Hodgkin's disease
MUTATION DATA - TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Human Cells - not otherwise specified
- DOSE/DURATION :
- 500 ug/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 32,2661,1972 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6647 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)
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Safety Information
| Hazard Codes | Xn:Harmful; |
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| Risk Phrases | R22 |
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| Safety Phrases | S36/37 |
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| WGK Germany | 3 |
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| RTECS | XZ4535000 |
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| HS Code | 29339990 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| MFCD00005233 |
| 3,5-diamino-1H-[1,2,4]-triazole |
| s-Triazole,3,5-diamino |
| 3,5-DiaMino-1,2,4-triazole |
| 1H-1,2,4-Triazole-3,5-diamine |
| EINECS 215-937-2 |
| GUANETIDINEHEMISULPHATE |
| 3,5-diamino-s-triazol |
| 3,5-Diamino-s-triazole |
| 4H-1,2,4-Triazole-3,5-diamine |
| GUANAZOLE |
