Introduction:Basic information about CAS 54417-53-7|R-Tetrahydropapaverine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | R-Tetrahydropapaverine |
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| CAS Number | 54417-53-7 | Molecular Weight | 379.88 |
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| Density | 1.12 g/cm3 | Boiling Point | 475.8ºC at 760 mmHg |
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| Molecular Formula | C20H26ClNO4 | Melting Point | / |
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| MSDS | / | Flash Point | 202.7ºC |
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Names
| Name | R-Tetrahydropapaverine |
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| Synonym | More Synonyms |
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R-Tetrahydropapaverine BiologicalActivity
| Description | (R)-Tetrahydropapaverine hydrochloride is the inactive isomer of Tetrahydropapaverine hydrochloride (HY-N0137), and can be used as an experimental control. Tetrahydropapaverine hydrochloride is one of the Tetrahydroisoquinolines. Tetrahydropapaverine hydrochloride has neurotoxic effects on dopamine neurons[1][2]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
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| References | [1]. Koshimura I, et al. Dimethoxyphenylethylamine and tetrahydropapaverine are toxic to the nigrostriatal system. Brain Res. 1997 Oct 31;773(1-2):108-16. [2]. Kim EI, et al. Inhibitory effects of tetrahydropapaverine on serotonin biosynthesis in murine mastocytoma P815 cells. Life Sci. 2004 Sep 3;75(16):1949-57. |
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Chemical & Physical Properties
| Density | 1.12 g/cm3 |
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| Boiling Point | 475.8ºC at 760 mmHg |
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| Molecular Formula | C20H26ClNO4 |
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| Molecular Weight | 379.88 |
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| Flash Point | 202.7ºC |
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| Exact Mass | 379.155029 |
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| PSA | 48.95000 |
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| LogP | 4.28130 |
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| Index of Refraction | 1.549 |
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| InChIKey | VMPLLPIDRGXFTQ-PKLMIRHRSA-N |
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| SMILES | COc1ccc(CC2NCCc3cc(OC)c(OC)cc32)cc1OC.Cl |
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Safety Information
| Hazard Codes | Xn:Harmful; |
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| Risk Phrases | R22;R52/53 |
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| Safety Phrases | S22-S61 |
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| HS Code | 2933499090 |
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Customs
| HS Code | 2933499090 |
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| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| (R)-(-)-Norlaudanosine Hydrochloride |
| (R)-1-((3,4-dimethoxyphenyyl)methyl)-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline hydrochloride |
| MFCD03788189 |
| (R)-Tetrahydropapaverinehydrochloride |
| EINECS 415-110-8 |
| R-(+)-TETRAHYDROPAPAVERIN HYDROCHLORIDE |
| http://www.gabrielpharm.com/hy/detailpro.phpid=39 |
| (R)-1,2,3,4-tetrahydropapaverine hydrochloride |
| (R)-tetrahydropaverine hydrochloride |
| Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride (1:1) |
| (R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquinoline hydrochloride |
| D-(-)-Norlaudanosine hydrochloride |
| (R)-1-(3,4-DIMETHOXY-BENZYL)-6,7-DIMETHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HCL |
| R-BINAP |
| 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride (1:1) |
| R-(+)-Tetrahydropapaverin |
| (r)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquinoline |
| R-(-)-norlaudanosine*HCl |
| R-tetrahydropapaverine HCl |