CAS 54417-53-7|R-Tetrahydropapaverine

Introduction:Basic information about CAS 54417-53-7|R-Tetrahydropapaverine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameR-Tetrahydropapaverine
CAS Number54417-53-7Molecular Weight379.88
Density1.12 g/cm3Boiling Point475.8ºC at 760 mmHg
Molecular FormulaC20H26ClNO4Melting Point/
MSDS/Flash Point202.7ºC

Names

NameR-Tetrahydropapaverine
SynonymMore Synonyms

R-Tetrahydropapaverine BiologicalActivity

Description(R)-Tetrahydropapaverine hydrochloride is the inactive isomer of Tetrahydropapaverine hydrochloride (HY-N0137), and can be used as an experimental control. Tetrahydropapaverine hydrochloride is one of the Tetrahydroisoquinolines. Tetrahydropapaverine hydrochloride has neurotoxic effects on dopamine neurons[1][2].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease
References

[1]. Koshimura I, et al. Dimethoxyphenylethylamine and tetrahydropapaverine are toxic to the nigrostriatal system. Brain Res. 1997 Oct 31;773(1-2):108-16.  

[2]. Kim EI, et al. Inhibitory effects of tetrahydropapaverine on serotonin biosynthesis in murine mastocytoma P815 cells. Life Sci. 2004 Sep 3;75(16):1949-57.  

Chemical & Physical Properties

Density1.12 g/cm3
Boiling Point475.8ºC at 760 mmHg
Molecular FormulaC20H26ClNO4
Molecular Weight379.88
Flash Point202.7ºC
Exact Mass379.155029
PSA48.95000
LogP4.28130
Index of Refraction1.549
InChIKeyVMPLLPIDRGXFTQ-PKLMIRHRSA-N
SMILESCOc1ccc(CC2NCCc3cc(OC)c(OC)cc32)cc1OC.Cl

Safety Information

Hazard CodesXn:Harmful;
Risk PhrasesR22;R52/53
Safety PhrasesS22-S61
HS Code2933499090

Customs

HS Code2933499090
Summary2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

(R)-(-)-Norlaudanosine Hydrochloride
(R)-1-((3,4-dimethoxyphenyyl)methyl)-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline hydrochloride
MFCD03788189
(R)-Tetrahydropapaverinehydrochloride
EINECS 415-110-8
R-(+)-TETRAHYDROPAPAVERIN HYDROCHLORIDE
http://www.gabrielpharm.com/hy/detailpro.phpid=39
(R)-1,2,3,4-tetrahydropapaverine hydrochloride
(R)-tetrahydropaverine hydrochloride
Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride (1:1)
(R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquinoline hydrochloride
D-(-)-Norlaudanosine hydrochloride
(R)-1-(3,4-DIMETHOXY-BENZYL)-6,7-DIMETHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HCL
R-BINAP
1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride (1:1)
R-(+)-Tetrahydropapaverin
(r)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquinoline
R-(-)-norlaudanosine*HCl
R-tetrahydropapaverine HCl
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