Introduction：Basic information about CAS 1205-30-7|4-Chloro-3-sulfamoylbenzoic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Chloro-3-sulfamoylbenzoic acid |
|---|
| CAS Number | 1205-30-7 | Molecular Weight | 235.645 |
|---|
| Density | 1.6±0.1 g/cm3 | Boiling Point | 502.4±60.0 °C at 760 mmHg |
|---|
| Molecular Formula | C7H6ClNO4S | Melting Point | 256-258 °C(lit.) |
|---|
| MSDS | ChineseUSA | Flash Point | 257.6±32.9 °C |
|---|
| Symbol |
GHS07 | Signal Word | Warning |
|---|
Names
| Name | 4-Chloro-5-sulphamoylbenzoic acid |
|---|
| Synonym | More Synonyms |
|---|
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|
| Boiling Point | 502.4±60.0 °C at 760 mmHg |
|---|
| Melting Point | 256-258 °C(lit.) |
|---|
| Molecular Formula | C7H6ClNO4S |
|---|
| Molecular Weight | 235.645 |
|---|
| Flash Point | 257.6±32.9 °C |
|---|
| Exact Mass | 234.970612 |
|---|
| PSA | 105.84000 |
|---|
| LogP | 0.92 |
|---|
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
|---|
| Index of Refraction | 1.622 |
|---|
| InChIKey | FHQAWINGVCDTTG-UHFFFAOYSA-N |
|---|
| SMILES | NS(=O)(=O)c1cc(C(=O)O)ccc1Cl |
|---|
| Storage condition | Refrigerator |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DG5642600
- CHEMICAL NAME :
- Benzoic acid, 4-chloro-3-sulfamoyl-
- CAS REGISTRY NUMBER :
- 1205-30-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C7-H6-Cl-N-O4-S
- MOLECULAR WEIGHT :
- 235.65
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 16,2275,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 16,2275,1982
|
Safety Information
| Symbol |
GHS07 |
|---|
| Signal Word | Warning |
|---|
| Hazard Statements | H315-H319-H335 |
|---|
| Precautionary Statements | P261-P305 + P351 + P338 |
|---|
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
|---|
| Hazard Codes | Xi:Irritant |
|---|
| Risk Phrases | R36/37/38 |
|---|
| Safety Phrases | S26-S37/39 |
|---|
| RIDADR | NONH for all modes of transport |
|---|
| WGK Germany | 3 |
|---|
| RTECS | DG5642600 |
|---|
Articles2
More Articles
| Studies on metabolism of tripamide. III. Metabolic fate of 14C-tripamide in rats and rabbits. Jpn. J. Pharmacol. 32(6) , 1041-9, (1982) The metabolic fate of a new antihypertensive agent, tripamide (N-(4-aza-endo-tricyclo[5.2.1.0(2,6))]-decan-4-yl)-4-chloro-3-sulfamoylbenzamide), in rats and rabbits was studied using its 14C-labeled c... | |
| Chromatographic-densitometric Method for Determination of Clopamide and 4-chlorobenzoic, and 4-chloro-3-sulfamoylbenzoic Acids in Tablets. Hubicka U, et al. Curr. Pharm. Anal. 5(4) , 408-15, (2009)
| |
Synonyms
| Benzoic acid, 3-(aminosulfonyl)-4-chloro- |
| EINECS 214-882-1 |
| 4-Chloro-3-sulfamoylbenzoic acid |
| MFCD00012375 |
| 3-(aminosulfonyl)-4-chlorobenzoic acid |
