CAS 43139-22-6|guanosine 5'-diphosphate sodium salt
| Common Name | guanosine 5'-diphosphate sodium salt | ||
|---|---|---|---|
| CAS Number | 43139-22-6 | Molecular Weight | 465.18200 |
| Density | / | Boiling Point | / |
| Molecular Formula | C10H14N5NaO11P2 | Melting Point | / |
| MSDS | USA | Flash Point | / |
Names
| Name | guanosine 5'-diphosphate sodium salt |
|---|---|
| Synonym | More Synonyms |
guanosine 5'-diphosphate sodium salt BiologicalActivity
| Description | Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate sodium is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate sodium can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2]. |
|---|---|
| Related Catalog | Research Areas >>Inflammation/ImmunologySignaling Pathways >>Membrane Transporter/Ion Channel >>Potassium Channel |
| Target | Human Endogenous Metabolite |
| References | [1]. S Kajioka, et al. Guanosine diphosphate activates an adenosine 5'-triphosphate-sensitive K+ channel in the rabbit portal vein. J Physiol. 1991 Dec;444:397-418. [2]. Angmo S, et al. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 Jan 5;7:40097. |
Chemical & Physical Properties
| Molecular Formula | C10H14N5NaO11P2 |
|---|---|
| Molecular Weight | 465.18200 |
| Exact Mass | 465.00600 |
| PSA | 275.02000 |
| InChIKey | RIVKOZCPUDVJCY-GWTDSMLYSA-N |
| SMILES | Nc1nc2c(ncn2C2OC(COP(=O)(O)OP(=O)(O)O)C(O)C2O)c(=O)[nH]1.[Na] |
| Storage condition | 20°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
Articles9
More Articles| A novel surface-confined glucaminium-based ionic liquid stationary phase for hydrophilic interaction/anion-exchange mixed-mode chromatography. J. Chromatogr. A. 1360 , 240-7, (2014) Glucaminium-based ionic liquids are a new class of recently developed ionic liquids and prepared by functionalizing the amine group of N-methyl-d-glucamine, which renders them good hydrophilicity due ... | |
| ROS production in brown adipose tissue mitochondria: the question of UCP1-dependence. Biochim. Biophys. Acta 1837(12) , 2017-30, (2014) Whether active UCP1 can reduce ROS production in brown-fat mitochondria is presently not settled. The issue is of principal significance, as it can be seen as a proof- or disproof-of-principle concern... | |
| Differential kinetics at PK/PEPCK branch point in the cestode, Raillietina echinobothrida. Exp. Parasitol. 153 , 151-9, (2015) Pyruvate kinase (PK; EC 2.7.1.40) and phosphoenolpyruvate carboxykinase (PEPCK; EC 4.1.1.32) are essential regulatory enzymes of glucose oxidation in helminths, the PK/PEPCK branch point being the fir... |
Synonyms
| guanosine 5'-diphosphate sodium salt,Type I |
| GUANOSINE-5'-DIPHOSPHATE MONOSODIUM SALT |
| guanosine 5'-diphosphate sodium type I |
| 5'-GDP 3NA |
| GUANOSINE-5'-DIPHOSPHATE SODIUM SALT ULTRA PURE GRADE |
| Guanosine-5''-diphosphoric acid monosodium salt |
