CAS 6805-34-1|Ferulenol

Introduction：Basic information about CAS 6805-34-1|Ferulenol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Ferulenol BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Ferulenol
CAS Number	6805-34-1	Molecular Weight	366.49300
Density	1.07g/cm3	Boiling Point	492.8ºC at 760 mmHg
Molecular Formula	C₂₄H₃₀O₃	Melting Point	/
MSDS	/	Flash Point	161.7ºC

Names

Name	4-hydroxy-3-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-2-one
Synonym	More Synonyms

Ferulenol BiologicalActivity

Description	Ferulenol, a sesquiterpene prenylated coumarin derivative, specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Ferulenol shows good antimycobacterial activity and haemorrhagic action[1][2][3].
Related Catalog	Research Areas >>Infection
In Vitro	Ferulenol inhibits the oxidative phosphorylation process by interacting with adenine nucleotide translocase (ANT) and the complex II of the respiratory chain. At low concentrations, ferulenol inhibited ATP synthesis by inhibition of the adenine nucleotide translocase without limitation of mitochondrial respiration. At higher concentrations, ferulenol inhibited oxygen consumption. Ferulenol caused specific inhibition of succinate ubiquinone reductase without altering succinate dehydrogenase activity of the complex II[1]. Ferulenol inhibits succinate ubiquinone reductase(SQR) activity in a concentration-dependent manner and is as effective as thenoyltrifluoroacetone (TTFA)[1].
References	[1]. Lahouel M, et al. Ferulenol specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Biochem Biophys Res Commun. 2007 Mar 30;355(1):252-7. [2]. Mamoci E, et al. Chemical composition and in vitro activity of plant extracts from Ferula communis and Dittrichia viscosa against postharvest fungi. Molecules. 2011 Mar 22;16(3):2609-25. [3]. DrissLamnaouer, et al. Ferulenol and ω-hydroxyferulenol, toxic coumarins from Ferula communis var. genuine. Volume 26, Issue 6, 1987, Pages 1613-1615.

Chemical & Physical Properties

Density	1.07g/cm3
Boiling Point	492.8ºC at 760 mmHg
Molecular Formula	C₂₄H₃₀O₃
Molecular Weight	366.49300
Flash Point	161.7ºC
Exact Mass	366.21900
PSA	50.44000
LogP	6.46030
Index of Refraction	1.559
InChIKey	NJJDBBUWWOAOLD-CFBAGHHKSA-N
SMILES	CC(C)=CCCC(C)=CCCC(C)=CCc1c(O)c2ccccc2oc1=O

Safety Information

HS Code	2932209090

Customs

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

4-hydroxy-3-(3,7,11-trimethyl-2,6,10-dodecatrienyl)-2H-1-benzopyran-2-one

Ferulenol

prenylated 4-hydroxycoumarin

E,E-3-farnesyl-4-hydroxycoumarin

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