Introduction：Basic information about CAS 2162-31-4|THP-PEG1-alcohol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | THP-PEG1-alcohol |
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| CAS Number | 2162-31-4 | Molecular Weight | 146.184 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 255.3±30.0 °C at 760 mmHg |
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| Molecular Formula | C7H14O3 | Melting Point | 95ºC 22 mm Hg(lit.) |
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| MSDS | / | Flash Point | 108.2±24.6 °C |
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Names
| Name | Tetrahydropyranylethyleneglycol |
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| Synonym | More Synonyms |
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THP-PEG1-alcohol BiologicalActivity
| Description | THP-PEG1-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 255.3±30.0 °C at 760 mmHg |
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| Melting Point | 95ºC 22 mm Hg(lit.) |
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| Molecular Formula | C7H14O3 |
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| Molecular Weight | 146.184 |
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| Flash Point | 108.2±24.6 °C |
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| Exact Mass | 146.094299 |
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| PSA | 38.69000 |
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| LogP | -0.38 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.460 |
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| InChIKey | XDBZJXRPEKFIFR-UHFFFAOYSA-N |
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| SMILES | OCCOC1CCCCO1 |
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Safety Information
| Safety Phrases | 23-24/25 |
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| WGK Germany | 3 |
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| HS Code | 2932999099 |
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Customs
| HS Code | 2932999099 |
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| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 2-(Tetrahydro-2H-pyran-2-yloxy)ethanol |
| Ethanol, 2-[(tetrahydro-2H-pyran-2-yl)oxy]- |
| 2-(oxan-2-yloxy)ethanol |
