CAS 1175-06-0|6-Keto cholestanol
| Common Name | 6-Keto cholestanol | ||
|---|---|---|---|
| CAS Number | 1175-06-0 | Molecular Weight | 402.65300 |
| Density | 1 g/cm3 | Boiling Point | 501.3ºC at 760 mmHg |
| Molecular Formula | C27H46O2 | Melting Point | 140-142 °C |
| MSDS | USA | Flash Point | 212.4ºC |
Names
| Name | 6-Keto Cholestanol |
|---|---|
| Synonym | More Synonyms |
6-Keto cholestanol BiologicalActivity
| Description | 6-Ketocholestanol is a recoupler for mitochondria, chromatophores and cytochrome oxidase proteoliposomes. 6-Ketocholestanol increases the membrane dipole potential[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Starkov AA, et al. 6-Ketocholestanol is a recoupler for mitochondria, chromatophores and cytochrome oxidase proteoliposomes. Biochim Biophys Acta. 1997 Jan 16;1318(1-2):159-72. |
Chemical & Physical Properties
| Density | 1 g/cm3 |
|---|---|
| Boiling Point | 501.3ºC at 760 mmHg |
| Melting Point | 140-142 °C |
| Molecular Formula | C27H46O2 |
| Molecular Weight | 402.65300 |
| Flash Point | 212.4ºC |
| Exact Mass | 402.35000 |
| PSA | 37.30000 |
| LogP | 6.64760 |
| Index of Refraction | 1.51 |
| InChIKey | JQMQKOQOLPGBBE-BHDMUPIRSA-N |
| SMILES | CC(C)CCCC(C)C1CCC2C3CC(=O)C4CC(O)CCC4(C)C3CCC12C |
| Storage condition | -20°C Freezer |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Risk Phrases | R24/25 |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles29
More Articles| SR4 Uncouples Mitochondrial Oxidative Phosphorylation, Modulates AMP-dependent Kinase (AMPK)-Mammalian Target of Rapamycin (mTOR) Signaling, and Inhibits Proliferation of HepG2 Hepatocarcinoma Cells. J. Biol. Chem. 290 , 30321-41, (2015) Mitochondrial oxidative phosphorylation produces most of the energy in aerobic cells by coupling respiration to the production of ATP. Mitochondrial uncouplers, which reduce the proton gradient across... | |
| Probing amphotericin B single channel activity by membrane dipole modifiers. PLoS ONE 7(1) , e30261, (2012) The effects of dipole modifiers and their structural analogs on the single channel activity of amphotericin B in sterol-containing planar phosphocholine membranes are studied. It is shown that the add... | |
| Effect of agents modifying the membrane dipole potential on properties of syringomycin E channels. Langmuir 23(13) , 6889-92, (2007) We evaluated the effect of agents modifying the membrane dipole potential: phloretin, 6-ketocholestanol and RH 421 on the properties of single channels formed by lipodepsipeptide syringomycin E (SRE) ... |
Synonyms
| MFCD00003572 |
| EINECS 214-640-5 |
| 6-ketocholestanol |
